Volume 11 Supplement 1

Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection

Meeting abstracts

Glasgow, UK9-13 November 2008

Page 1 of 8

Clinical effect of interleukin-2 (IL-2) immuno-adjuvant treatment in HIV+ advanced naïve patients

Authors: C Tincati, M Cesari, L Meroni, F Bai, GM Bellistrì, M Galli, ME Moroni, A d'Arminio Monforte and GM Marchetti

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P1

Content type: Poster presentation Published on: 10 November 2008
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O111 Global impact of HIV drug resistance

Authors: D Pillay

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O1

Content type: Oral presentation Published on: 10 November 2008
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Pathogenesis of HIV infection: implications for treatment and prevention

Authors: HC Lane

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):K1

Content type: Keynote presentation Published on: 10 November 2008
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O112 Trends in transmitted HIV drug resistance among non-B subtypes in the UK

Authors: D Chilton, L Harrison, H Green, S Lattimore, V Delpech and D Pillay

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O2

Content type: Oral presentation Published on: 10 November 2008
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Efficacy and safety of TMC278 in treatment-naïve, HIV-infected patients: week 96 data from TMC278-C204

Authors: JM Molina, C Cordes, P Ive, A Vibhagool, S Vanveggel, P Williams and K Boven

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P2

Content type: Poster presentation Published on: 10 November 2008
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How will we use the new ART drugs?

Authors: C Katlama

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):K2

Content type: Keynote presentation Published on: 10 November 2008
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Impact of antiretroviral dosing and daily pill burden on viral rebound rates in naive patients receiving a tenofovir-based regimen

Authors: A Ammassari, P Lorenzini, F Maggiolo, G Sterrantino, A Corpolongo, G Rizzardini, N Abrescia, A Chirianni, M Foggia, C Mussini, N Gianotti, M Andreoni, CF Perno and A Antinori

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P3

Content type: Poster presentation Published on: 10 November 2008
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O113 HIV-1 clade C resistance genotypes after first virological failure in a large community ART programme

Authors: C Orrell, RP Walensky, E Losina, KA Freedberg and R Wood

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O3

Content type: Oral presentation Published on: 10 November 2008
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The implications beyond public health if we don't manage the HIV epidemic

Authors: A Whiteside

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):K3

Content type: Keynote presentation Published on: 10 November 2008
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The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz in antiretroviral-naïve patients through 7 years

Authors: JVR Madruga, I Cassetti, A Etzel, JMA Suleiman, Y Zhou, AK Cheng and J Enejosa

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P4

Content type: Poster presentation Published on: 10 November 2008
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O114 NNRTI mutations are efficiently transmitted within clusters of new HIV infections

Authors: BG Brenner, T d'Aquin Toni, M Roger, JP Routy, D Moisi and MA Wainberg

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O4

Content type: Oral presentation Published on: 10 November 2008
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Effects of NRTI backbone on HIV RNA, CD4 counts and lipids for first-line boosted PI-based HAART: meta-analysis of 12 clinical trials in 4,896 patients

Authors: AM Hill and WA Sawyer

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P5

Content type: Poster presentation Published on: 10 November 2008
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O115 Importance of detecting minority variants in the clinical management of HIV

Authors: D Kuritzkes

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O5

Content type: Oral presentation Published on: 10 November 2008
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A study to evaluate the efficacy, safety and tolerability of co-administered lopinavir/ritonavir (LPVr) and nevirapine (NVP) in HIV-infected adults

Authors: TW Mahungu, LJ Else, CJ Smith, Z Cuthbertson, D Podlekareva, P Hay, UB Dragsted, SH Khoo, MA Johnson, DJ Back and M Youle

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P6

Content type: Poster presentation Published on: 10 November 2008
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O121 Drug interactions that really matter

Authors: SH Khoo

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O6

Content type: Oral presentation Published on: 10 November 2008
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Similar virological response rates for ART-naïve subjects starting KVX + LPV/r or TVD+ LPV/r. Data from the prospective observational STAR cohort

Authors: E Wolf, A Trein, W Schmidt, A Baumgarten, H Jaeger and HJ Stellbrink

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P7

Content type: Poster presentation Published on: 10 November 2008
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O122 Prevalence of drug interactions between antiretroviral and co-administered drugs at the Moi teaching and referral hospital (Ampath), Eldoret, Kenya

Authors: GK Kigen, S Kimaiyo, DJ Back, SE Gibbons, E Sang, IG Edwards, A Owen and SH Khoo

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O7

Content type: Oral presentation Published on: 10 November 2008
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Efficacy and safety by baseline HIV-RNA and CD4 count in treatment-naive patients treated With atazanavir/r and lopinavir/r in the CASTLE study

Authors: J Uy, R Yang, A Thiry, J Absalon, A Farajallah, JF Maa and D McGrath

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P8

Content type: Poster presentation Published on: 10 November 2008
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O123 To overdose or underdose? The question of Kaletra in children in the UK/Irish Collaborative HIV Paediatric Study (CHIPS)

Authors: AS Walker, KL Boyd, K Doerholt, H Lyall, E Menson, K Butler, P Tookey, A Riordan, D Shingadia, A Judd, G Tudor-Williams and DM Gibb

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O8

Content type: Oral presentation Published on: 10 November 2008
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Differences in CD4 count increases in veterans starting antiretroviral therapy with lopinavir/ritonavir or efavirenz

Authors: RJ Bedimo, H Drechsler, M Holodniy, M Pasley and W Woodward

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P9

Content type: Poster presentation Published on: 10 November 2008
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O124 Efavirenz and rifampicin in the South African context: is there a need to dose increase efavirenz with concurrent rifampicin therapy?

Authors: C Orrell, K Cohen, P Ive, I Sanne and R Wood

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O9

Content type: Oral presentation Published on: 10 November 2008
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Immune restoration during HAART: 8-year follow-up in HIV-positive patients with sustained virological suppression

Authors: L Malincarne, A Sgrelli, G Camanni, R Papili, D Francisci and F Baldelli

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P10

Content type: Poster presentation Published on: 10 November 2008
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O125 Impact of efavirenz and nevirapine on pharmacokinetics of lopinavir/ritonavir as tablets and capsules in African patients

Authors: C Kityo, AS Walker, F Lutwana, F Ssali, R Nalumenya, D Tumukunde, J Kawiya, P Munderi, A Reid, CF Gilks, DM Gibb and SH Khoo

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O10

Content type: Oral presentation Published on: 10 November 2008
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Evaluating affordable screening markers to detect HIV-1-infected Ugandan adults with CD4 counts of less than 200 cells/mul

Authors: GM Miiro, J Todd, S Nakubulwa, C Watera, P Hughes, P Munderi, S Floyd and H Grosskurth

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P11

Content type: Poster presentation Published on: 10 November 2008
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O132 Secondline ART in the developing world

Authors: J Hakim

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O11

Content type: Oral presentation Published on: 10 November 2008
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Efficacy and safety of TDF/FTC-containing first-line HAART in clinical practice – 2-year data from the German Outpatient Cohort

Authors: J van Lunzen, G Fätkenheuer, T Lutz, S Klauke, S Mauss, H Knechten, P Braun, L Gallo and B Ranneberg

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P12

Content type: Poster presentation Published on: 10 November 2008
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O131 Where are we with National and International guidelines?

Authors: E Katabira

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O12

Content type: Oral presentation Published on: 10 November 2008
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The Rainbow Cohort: saquinavir/r is effective and well tolerated in antiretroviral therapy (ART)-naïve patients – 48-week results from Germany

Authors: H Knechten, C Stephan, T Lutz, A Stoehr, A Carganico, G Knecht, K Schewe, H Jaeger, C Mayr, FA Mosthaf, E Wolf, E Wellmann and A Tappe

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P13

Content type: Poster presentation Published on: 10 November 2008
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O135 Seek and treat for optimal prevention of HIV/AIDS (STOP HIV/AIDS)

Authors: JSG Montaner

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O13

Content type: Oral presentation Published on: 10 November 2008
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Comparing the efficacy of Truvada^® and Kivexa^® combination therapy in HAART-naive individuals with different viral loads

Authors: RH Daniels, BG Gazzard, P Holmes, A Scourfield, M Bower and M Nelson

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P14

Content type: Poster presentation Published on: 10 November 2008
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O133 HIV/TB: when is it safe to start HAART?

Authors: R Wood

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O14

Content type: Oral presentation Published on: 10 November 2008
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The TOKEN study: safety and efficacy of Truvada or Kivexa in combination with efavirenz in treatment-naïve predominantly black African HIV patients

Authors: S Das, J Arumainayagam, B Kumari, S Chandramani, L Riddell and M Ghanem

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P15

Content type: Poster presentation Published on: 10 November 2008
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O134 HIV disease management and challenges in Eastern Europe and Central Asia

Authors: A Bobrik

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O15

Content type: Oral presentation Published on: 10 November 2008
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Experience with ritonavir/atazanavir in HIV-positive antiretroviral-naïve individuals commencing therapy

Authors: B Graf, K Taylor, A Gupta, BG Gazzard and M Nelson

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P16

Content type: Poster presentation Published on: 10 November 2008
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O211 HIV and the brain: neuro-inflammation long-term, CNS control of HIV replication, brain disease in suppressed patients and differential penetration of drugs

Authors: D Clifford

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O16

Content type: Oral presentation Published on: 10 November 2008
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HAART in HIV+ naive elderly patients: immuno-virological response and clinical outcome

Authors: BM Celesia, F Bisicchia, R La Rosa, S Mavilla, M Gussio, MT Mughini, F Palermo and R Russo

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P17

Content type: Poster presentation Published on: 10 November 2008
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O212 Rate of change in CD4 counts in patients with stable HIV viremia

Authors: AN Phillips, B Ledergerber, JR Bogner, K Lacombe, A Wiercinska-Drapalo, P Reiss, O Kirk, JD Lundgren and A Mocroft

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O17

Content type: Oral presentation Published on: 10 November 2008
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Nevirapine (NVP), tenofovir (TDF) and lamivudine (3TC) or emtricitabine (FTC) is effective and well tolerated in naïve HIV-1 infected patients

Authors: M Bickel, P Gute, A Carlebach, A Mueller and S Klauke

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P18

Content type: Poster presentation Published on: 10 November 2008
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O213 CD4-guided STI in patients responding to HAART

Authors: F Maggiolo, M Airoldi, A Callegaro, C Martinelli, A Dolara, T Bini, G Gregis, P Quinzan, V Ravasio and F Suter

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O18

Content type: Oral presentation Published on: 10 November 2008
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Comparison of the efficacy at 48 weeks of first-line antiretroviral treatment for HIV infection in 1998 and 2006: a multicentric investigation

Authors: F Sozio, V Soddu, G De Socio, M D'Alessandro, E Polilli, G Madeddu, P Bonfanti, E Mazzotta, J Vecchiet, MS Mura, T Quirino, L Manzoli and G Parruti

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P19

Content type: Poster presentation Published on: 10 November 2008
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O214 The FOTO study: 24-week results support the safety of a 2-day break on efavirenz-based antiretroviral therapy

Authors: C Cohen, A Colson, G Pierone, E DeJesus, F Kinder, R Elion, D Skiest, A Habel, J Jensen, J Garb and H Schrager

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O19

Content type: Oral presentation Published on: 10 November 2008
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Raltegravir: a potent and safe integrase inhibitor with a favourable impact on cardiovascular and liver profile

Authors: F Blanco, M Arredondo, F Guevara, C Garrido, J Morello, S Rodríguez-Nóvoa, M Córdoba, J González-Lahoz and V Soriano

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P20

Content type: Poster presentation Published on: 10 November 2008
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O221 Optimising paediatric treatment for long term survival. Adult survivors of congenital HIV infection – what problems will they have?

Authors: H Lyall

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O20

Content type: Oral presentation Published on: 10 November 2008
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POWER 1 and 2: combined final 144-week efficacy and safety results for darunavir/ritonavir (DRV/r) 600/100 mg BID in treatment-experienced HIV patients

Authors: C Katlama, N Bellos, B Grinsztejn, A Lazzarin, A Pozniak, S De Meyer, T Van De Casteele and S Spinosa-Guzman

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P21

Content type: Poster presentation Published on: 10 November 2008
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O222 Treatment interruption in children with chronic HIV-infection: the results of the paediatric European network for treatment of AIDS (PENTA) 11 trial

Authors: DM Gibb, A Compagnucci, H Green, M Lallemant, Y Saidi, N Ngo-Giang-Huong, C Taylor, L Mofenson, F Monpoux, MIG Tomé, M Marczyñska, D Nadal, U Wintergerst, S Kanjavanit, H Lyall, C Giaquinto…

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O21

Content type: Oral presentation Published on: 10 November 2008
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Phase III TITAN week 96 final analysis: efficacy/safety of darunavir/r (DRV/r) vs. lopinavir/r (LPV/r) in LPV-naïve, treatment-experienced patients

Authors: D Bánhegyi, C Katlama, C Da Cunha, S Schneider, A Rachlis, O Romanenko, C Workman, A Vandevoorde, F Tomaka, T Vangeneugden and S Spinosa-Guzman

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P22

Content type: Poster presentation Published on: 10 November 2008
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O223 Antiretroviral Pregnancy Registry (APR) at 10,000 prospective reports

Authors: KP Beckerman, D Covington, K Dominguez, A Scheuerle, VX Vannappagari, DH Watts and H Tilson

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O22

Content type: Oral presentation Published on: 10 November 2008
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Virological response with fully active etravirine (ETR; TMC125) after 48 weeks of treatment: pooled results from the DUET-1 and DUET-2 trials

Authors: N Clumeck, B Clotet, MA Johnson, M Peeters, J Vingerhoets, G Beets and G De Smedt

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P23

Content type: Poster presentation Published on: 10 November 2008
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O224 The early AIDS epidemic in the U.S.: views from Atlanta and Hollywood

Authors: H Jaffe

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):O23

Content type: Oral presentation Published on: 10 November 2008
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POWER 3 analysis: 144-week efficacy and safety results for darunavir/ritonavir (DRV/r) 600/100 mg BID in treatment-experienced HIV patients

Authors: A Pozniak, K Arastéh, JM Molina, B Grinsztejn, S De Meyer, T Van De Casteele and S Spinosa-Guzman

Citation: Journal of the International AIDS Society 2008 11(Suppl 1):P24

Content type: Poster presentation Published on: 10 November 2008
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Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection

Meeting abstracts

Journal of the International AIDS Society