- Poster presentation
- Open Access
Impairment of functional integrity of the vasculature is not changed in patients starting abacavir
© Zona et al; licensee BioMed Central Ltd. 2008
- Published: 10 November 2008
- Cardiovascular Disease
- Observational Study
- Endothelial Function
- Disease Risk
- Drug Regimen
In order to explore a possible pathogenetic mechanism of abacavir (ABC) cardiovascular toxicity, we assess the impact of beginning the drug on endothelial function via assessment of brachial artery diameter (BAD) and flow-mediated dilation (FMD).
Cross-sectional observational study that included all consecutive HIV-infected patients seen at a metabolic clinic who had BAD and FMD evaluation before and 9 months after beginning ABC as a component of a new drug regimen.
Change in impairment of functional integrity of the vasculature is not an associated factor related with ABC use. Cardiovascular disease risk among HIV-infected HAART-experienced persons is likely governed by complex pathophysiologic and treatment factors.
This article is published under license to BioMed Central Ltd.