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Journal of the International AIDS Society

Open Access

Age-related co-morbidities in people living with HIV

  • G Guaraldi1,
  • S Zona1,
  • G Orlando1,
  • N Squillace1,
  • C Stentarelli1,
  • G Nardini1,
  • B Beghetto1,
  • R Esposito1 and
  • FJ Palella2
Journal of the International AIDS Society200811(Suppl 1):P300

Published: 10 November 2008


Kidney DiseaseAging PopulationElderly PeopleDrug ClassSpecific Drug

Purpose of the study

To describe prevalence of age-related morbidities across age groups in people living with HIV/AIDS and analyze care needs in the elderly people.


Consecutive patients attending a metabolic clinic. Body fat changes, metabolic, cardiovascular, endocrine and renal morbidities were identified as relevant medical conditions requiring drug intervention (either switch of ARVs or introduction of specific drug classes).

Summary of results

ANOVA was used for means and chi-square test for proportions except:

* Kruskal-Wallis

* Fisher's exact

Prevalence of three or more co-morbidities in the age group were: 7.89% for age ≤30, 24.68% for age 30–40, 33.72% for age 40–50, 49.01% for age 50–60 and 60.87% for age >60 years. (Figure 1.)


Metabolic, cardiovascular, endocrine, hepatic and kidney disease are age-associated conditions highly prevalent in people living with HIV. Multiple co-morbidities increase with age and witness the multidisciplinary care needs of the HIV aging population.

Figure 1

Authors’ Affiliations

University of Modena and Reggio Emilia, Modena, Italy
Northwestern University, Feinberg School of Medicine, Chicago, USA


© Guaraldi et al; licensee BioMed Central Ltd. 2008

This article is published under license to BioMed Central Ltd.