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Prevalence of cardiovascular risk factors in Spanish HIV-1-infected male inmates
© Golf et al; licensee BioMed Central Ltd. 2010
Published: 8 November 2010
Purpose of the study
HIV-1-infected inmates have an increased prevalence of some particular comorbidities. However, the cardiovascular risk(CVR) of this population has rarely been evaluated.
Cross-sectional study carried out among 216 male HIV-1 patients in prison. Patients were stratified according to age(<34, 35-39, 40-44, 45-49, 50-54 and >55 years old, respectively)and their CVR was assessed by Framingham(FRAM) equation. The prevalence of some further risk factors was also evaluated: time on antiretroviral therapy, nadir CD4 count, maximum viral load(VL), time on undetectable VL, HCV-coinfection, and cocaine use.
Cardiovascular risk factors prevalence stratified by age group.
Tot Chol > 200
HDL Chol <39
Using the FRAM scores, the median CVR of developing a cardiac event at 10 years in a population of Spanish HIV-1-infected inmate males is 5.88%. Of them, 5.1% have a high CVR, and are evenly distributed among age groups. The smoking prevalence is significantly higher than in non-inmate HIV-1 infected individuals, and is so high that it does not allow CVR differences among age groups. HCV-coinfection, cocaine use, and parenteral cocaine consumption were not associated with an increased CVR in our population. On the other hand, a lower nadir CD4 count was associated with high rates of CVR, thus supporting an earlier initiation of ARV therapy in HIV-1 infected males in the prison environment.
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.