Table 1
From: Herb-drug interaction between Echinacea purpurea and darunavir/ritonavir in HIV-infected patients
DRV/r | DRV/r + Echinacea | GMR (95% CI) | p | |
|---|---|---|---|---|
Cτ (ng/mL) | 2.1 (1.6-2.7) | 1.7 (1.4-2.2) | 0.84 (0.59-1.19) | 0.311 |
AUCτ (ng.h/mL) | 46.2 (39.0-54.7) | 41.6 (35.1-49.2) | 0.90 (0.71-1.14) | 0.374 |
Cmax (ng/mL) | 6.4 (5.5-7.4) | 6.2 (5.3-7.25) | 0.98 (0.79-1.21) | 0.810 |