- Open Access
Associations between depressive symptoms, sexual behaviour and relationship characteristics: a prospective cohort study of young women and men in the Eastern Cape, South Africa
© Nduna et al. 2010
- Received: 14 April 2010
- Accepted: 15 November 2010
- Published: 15 November 2010
Psychological factors are often neglected in HIV research, although psychological distress is common in low- to middle-income countries, such as South Africa. There is a need to deepen our understanding of the role of mental health factors in the HIV epidemic. We set out to investigate whether baseline depressive symptomatology was associated with risky sexual behaviour and relationship characteristics of men and women at baseline, as well as those found 12 months later.
We used prospective cohort data from a cluster randomized controlled trial of an HIV prevention intervention in the Eastern Cape Province of South Africa. Our subjects were 1002 female and 976 male volunteers aged 15 to 26. Logistic regression was used to model the cross-sectional and prospective associations between baseline depressive symptomatology, risky sexual behaviors and relationship characteristics. The analysis adjusted for the clustering effect, study design, intervention and several confounding variables.
Prevalence of depressive symptoms was 21.1% among women and 13.6% among men. At baseline, women with depressed symptoms were more likely to report lifetime intimate partner violence (AOR = 2.56, 95% CI 1.89-3.46) and have dated an older partner (AOR = 1.37, 95% CI 1.03-1.83). A year later, baseline depressive symptomatology was associated with transactional sex (AOR = 2.60, 95% CI 1.37, 4.92) and intimate partner violence (AOR = 1.67, 95% CI 1.18-2.36) in the previous 12 months. Men with depressive symptoms were more likely to report ever having had transactional sex (AOR = 1.48, 95% CI 1.01-2.17), intimate partner violence perpetration (AOR = 1.50, 95% CI 0.98-2.28) and perpetration of rape (AOR = 1.81, 95% CI 1.14-2.87). They were less likely to report correct condom use at last sex (AOR = 0.50, 95% CI 0.32-0.78). A year later, baseline depressive symptomatology was associated with failure to use a condom at last sex among men (AOR = 0.60, 95% CI 0.40-0.89).
Symptoms of depression should be considered as potential markers of increased HIV risk and this association may be causal. HIV prevention needs to encompass promotion of adolescent mental health.
- Depressive Symptom
- Intimate Partner Violence
- Sexual Risk
- Risky Sexual Behaviour
- Depressive Symptomatology
The HIV epidemic is continuing to expand globally as prevention efforts show limited success in many population groups [1–3]. Research from southern Africa on risky sexual behaviours and relationships in which HIV transmission may occur emphasizes social, cultural, political and economic factors to the neglect of psychological factors [4–7]. Yet psychological distress is common in low- to middle-income countries , such as South Africa [9–12]. Evidence that social circumstances and knowledge do not explain sexual risk behaviours alone suggests that we need to deepen our understanding of the role of mental health factors in the HIV epidemic [13–17].
Research has found depressive symptomatology among youth to be associated with earlier sexual debut, higher numbers of lifetime sexual partners, concurrent, multiple and casual sexual partnerships, substance use at last sex, pregnancy, non-use of contraception, perceived barriers to condom use and having more risky partners [16, 18–28]. However, most of this evidence comes from high-income countries, and these associations have not been established in South Africa or other countries with generalized HIV epidemics.
In South Africa, there is conflicting evidence on the association of depressive symptomatology with condom use, with one study showing greater use of condoms among respondents with depressed symptoms  and another reporting the opposite . A community-based cross-sectional study from South Africa confirmed the associations between depression and having concurrent partnerships, previous treatment for a sexually transmitted infection, sex with someone known for less than one day, sex while using alcohol or drugs, transactional sex and forced sex .
This study was carried out with a general adult population sample and did not disaggregate findings by age or gender, leaving open questions as to any differences between women and men, and associations among adolescents. The objective of our study was to investigate the association between baseline depressive symptomatology, and sexual behaviour and relationship characteristics both at baseline and 12 months later among young women and men in the rural parts of the Eastern Cape Province of South Africa.
Between 2002 and 2004 a cohort of young women and men participated in the Stepping Stones Study, a cluster randomized trial to evaluate the effectiveness of a behavioural prevention intervention for HIV [29, 30]. The study was conducted in 70 sites (clusters) around the small city of Mthatha. These were grouped into seven strata: an urban stratum and six rural strata. Participants were volunteers aged 15 to 26 who resided in the clusters. Participants were interviewed at baseline, invited to attend one of the two study arms and then re-interviewed 12 and 24 months later. Methodology, recruitment, characteristics of the study site and main trial findings are described elsewhere [29, 30]. Ethical approval for the Stepping Stones Study was granted by the University of Pretoria and University of Witwatersrand.
All interviews were conducted by highly trained young, sex-matched interviewers to achieve more open disclosure of sexual behaviours. A standardized structured questionnaire administered in isiXhosa, the local language, was used to collect data in one-on-one, face-to-face interviews. A year later, 1002 (78%) women and 976 (76%) men were re-interviewed. The two main reasons for loss to follow up were relocation and death .
The questionnaire asked about date of birth and highest school grade passed. Age in years was treated as a continuous variable. Education was dichotomized into "educated up to Grade 10 versus further". Alcohol abuse was measured using the AUDIT Alcohol Screening Test and a cut-off point of 8 indicated a drinking problem . Socio-economic status was measured using questions developed for this study that captured household goods ownership (TV, radio, car), food and meat availability, and access to a modest sum of R100 (US$13 in 2010) for medical emergency. A higher score reflected greater wealth. For women, the Cronbach's alpha was 0.55, and for men 0.60.
Childhood adversity was assessed using a 23-item revised Childhood Trauma Questionnaire, which measured emotional and physical neglect, and emotional, physical and sexual abuse [32, 33]. Participants were asked whether, before the age of 18, they had experienced each act never, sometimes, often or very often. A typical item read, "I was beaten so hard at home that it left a mark or bruise." A higher score reflected more trauma experienced. The Cronbach's alphas were 0.77 in women and 0.75 in men.
Participants were asked their age at first sex, referring to penetrative vaginal sex, and whether this sexual experience was willing, persuaded, tricked, forced or rape. First sexual experience was dichotomized into: "willing, persuaded and tricked" versus "forced or raped". All were asked if they had ever used a condom. Women were asked if they had ever been pregnant or were pregnant at the time of the interview, and men were asked if they have been told by any of their sexual partners that they had made them pregnant.
Depressive symptoms were measured using the Centre for Epidemiological Studies on Depression (CES D) Scale . This is a common screening scale measuring feelings and behaviours characteristic of symptoms of depression during the past week. It consists of 20 items scored from rarely experienced (0) to experienced most or all of the time (3). A typical item read, "During the past week, I was bothered by things that usually don't bother me." Scores ranged from 0 to 60, and 16+ was used as a cut-off point for probable depressive caseness . This tool has been previously used in South Africa for community-based research studies [10, 35]. The Cronbach's alpha for women was 0.90 and 0.91 for men.
Outcome variables: sexual behaviours and relationship characteristics
At baseline, information about sexual behaviours and relationships was reported for lifetime or current status, and at follow up, it was recorded for the period since the last interview or in the past 12 months. Participants reported the number of main and casual sexual partners, and a total of three or more partners were used as our "high" category. Women were asked the age of their main partner and the difference between this and their own age was calculated. We considered a woman to have had an older partner if he was three or more years older . We asked about correct condom use with the main partner at last sex, defined as the condom not breaking, slipping off, not put on during the sexual act, or removed prematurely.
Knowledge of partner concurrency was assessed by a question, "How likely do you think it is that (NAME OF PARTNER) is having sex with someone else - would you say definitely is, probably is, probably is not or definitely not?" Responses were dichotomized into "definitely or probably is non-monogamous" or "probably or definitely is monogamous". We asked respondents about engaging in transactional sex using questions that have been used in similar settings . Transactional relationships were defined as those where material gain was the main motivating factor for the relationship or sexual encounter with a main, casual or one-night stand partner. For women, the questions were about receiving, and for men, about both giving to a woman and receiving from a woman.
Relationship control was measured on 13-item modified version of the Sexual Relationship Power Scale . A typical item from the scale (answerable in "strongly agree", "agree", "disagree", "strongly disagree") was, "When (NAME OF BOYFRIEND) wants me to sleep over, he expects me to agree." For men, the reverse read, "When I want (NAME OF GIRLFRIEND) to sleep over, I expect her to agree." A higher score meant there was equitable power sharing in the relationship. The Cronbach's alpha for women was 0.68; for men, it was 0.54.
Questions on intimate partner violence (IPV) were adapted from the World Health Organization instrument; they asked women about experiencing violence and men about perpetrating violence . The IPV questions inquired about specific physically violent practices: pushed, shoved, slapped, hit with fist, kicked, beaten up, strangled, burnt, hurt/threatened with a weapon, and threw something that could hurt her, as well as their frequency. Sexual IPV questions asked about forced sex or sex performed because the woman was afraid of negative consequences. Based on prior research in this setting, a variable measuring IPV exposure was derived, which dichotomized it as zero or one episode versus two or more episodes. Men were additionally considered to have raped a non-partner if they responded affirmatively to any question on individually or group-perpetrated rape of a woman who was not a girlfriend. An example of items measuring non-partner rape is, "Was there a time when you made a woman or girl, other than your girlfriend at the time, have sex with you when she did not want to?"
Data were analyzed using StataIC 11. All analyses took into account the study design with the dataset viewed as a cohort, and a stratified, two-stage structure with participants clustered within the 70 study sites . Data were analyzed separately for women and men . Analysis was restricted to only those participants who had had sex at baseline, and at follow up, to those who had had sex in the previous 12 months.
Baseline characteristics of lost to follow up and the remaining cohort: women and men
Lost to follow up
Lost to follow up
n = 293
n = 1002
n = 312
n = 976
Socio-economic status score
-0.06 (-3.06, 3.31)
-0.01 (-3.06, 3.84)
-0.11 (-2.91, 3.52)
0.03 (-2.91, 3.52)
Adverse childhoods score
0.01 (-1.28, 3.81)
0.04 (-1.28, 6.34)
0.09 (-1.29, 5.09)
-0.03 (-1.29, 9.41)
Age at first sex
Educated up to Grade 10
First sex experience was willing
Ever used a condom
Ever been pregnant
To test the hypothesis that baseline depressive symptomatology was associated with sexual risk, we built logistic regression models adjusting for study design and controlled for possible confounding variables that were chosen on the basis of literature [20, 41–45]. The confounding variables adjusted for were socio-economic status, experiences of childhood adversity, alcohol abuse and education. A separate model was build for each variable.
To test the hypothesis that baseline depressive symptomatology was associated with subsequent sexual risk, we built logistic regression models that controlled for the baseline level of each variable, the intervention arm and study design. We tested for interaction between depression and intervention arm, and preset the adjusted ORs for this where the effect was more than 10%.
Sample background and socio-demographic characteristics
Background demographic characteristics for women and men
WOMEN (n = 1294)
MEN (n = 1288)
No depressed mood
No depressed mood
Educated up to grade 10
Alcohol use problem
Socio-economic status score
-0.24 (-3.06, 3.84)
.03 (-3.06, 3.84)
-0.08 (-2.91, 3.52)
Experience of adverse childhood
0.47 (-1.28, 4.19)
-0.07 (-1.28, 6.34)
-0.10 (-1.29, 5.41)
Age at first sex
Ever used a condom
Ever been pregnant
Depressive symptoms, sexual behaviour and relationship characteristics
Associations between depressive symptoms, sexual behaviours and relationship characteristics for women
n = 1294
12 months later
n = 995
3+ lifetime sexual partners
[AOR2 past year]
More liberal power dynamics in the relationship vs. less liberal
Partner has other partner(s)
Had a main partner who was 3+ years older
Correct condom use with main partner at last sex
2 or more episodes of physical or sexual abuse
Associations between depressive symptoms, sexual behaviours and relationship characteristics for men
n = 1288
12 months later
n = 984
3+ lifetime sexual partners
[AOR2 last year]
More liberal power dynamics in the relationship vs. less liberal
Partner has another partner(s)
Correct condom use with main partner at last sex
2 or more episodes of physical or sexual abuse
Stranger rape perpetration
Our findings show that depressive symptoms are associated with behaviours and relationship characteristics that put young South African women and men at risk for sexually transmitted HIV. For women, having depressive symptoms was associated with having experienced one or more incidents of physical or sexual IPV and dating a partner three or more years older, as well as a greater likelihood over the following 12 months of having transactional sex and experiencing further IPV.
In men, depressive symptoms at baseline were associated with having had transactional sex, not using a condom or doing so incorrectly at last intercourse, and having raped a stranger or acquaintance; there was some evidence suggesting that they were also associated with having perpetrated more than one episode of physical or sexual IPV. Men who reported baseline depressive symptoms were at greater likelihood of not using a condom or doing so incorrectly at last intercourse 12 months later. While baseline associations can be bidirectional, and we have no knowledge of the duration of how depressive symptomatology, the associations found in the prospective analysis confirm that depressive mood predicted sexual risk 12 months later.
Intimate partner violence victimization and perpetration were associated with depressed symptoms in both the cross-sectional and prospective analyses. It is known that, for women, being in an abusive relationship causes depression [46, 47], and our prospective findings show that a depressive state predicted vulnerability to abuse and to a controlling partner, a situation that is likely to generate more depressive symptoms. Addressing IPV in HIV is important as it has been shown to increase risky sexual behaviours and risk of HIV infections [33, 36, 47–51]. Baseline findings here measured past and current IPV, suggesting therefore that prevention of violence could have prevented baseline depressive symptoms. Evidence presented here suggests that the presence of depressive symptoms was associated with both sexual victimization of males and male rape perpetration. This is in agreement with previous research .
Male condoms are widely and freely available in South Africa and condom use is an act that is mainly male-controlled . There are many reasons for young adults not to use condoms, including preference for sex without one, trusting a partner, a belief in the safety of a steady relationship, lack of persuasive power, relationship conflict, and, for women, gender inequity and fear of violence [14, 15, 52–55]. It is possible that feelings of helplessness and hopelessness associated with depression reduce men's interest in, or determination around, protective behaviour. This study shows that promoting mental health needs to be recognized as important for condom use promotion.
In this study, depressive symptomatology was associated with dating a man three or more years older for young women, and this is an important risk factor because HIV prevalence in older men in this setting is higher [36, 56, 57]. Important social factors increasing young women's vulnerability to HIV in relationships with older men are gender power inequalities, IPV and transactional sex [58–60]. Young women with depressive symptoms may try to please their partners, becoming unassertive and more vulnerable to abuse, especially if the primary motivation for the relationship was material gain. In the baseline analysis, it is not possible to know if depressive symptomatology preceded having older male partners or followed them. However, the study findings suggested that family-level financial hardships and dating older partners need to be addressed together in HIV prevention programming and these should integrate interventions aimed at reducing depressive symptoms.
These findings are useful in helping us understand the interactions between depressive symptoms and sexual risk. The study participants were recruited for an HIV behavioural intervention evaluation and there may have been under-reporting of sexual risk taking, but we attempted to reduce this bias by standardizing measurements, fieldworker training and most of the baseline data being collected by four interviewers. The use of different questions to measure the outcome by asking about the current or most recent partners and actions provided a robust way to maximize recall. To encourage more honest disclosure by participants, we assured them of confidentiality, communicated survey legitimacy, and ensured rapport between interviewer and respondents; these are all taken to encourage accurate disclosure in survey interviews of sexual behaviours . Field workers had no knowledge of baseline depressive symptomatology when interviewing at 12 months.
As HIV risk in late adolescence continues to be a serious concern in southern Africa [13, 32, 60], this study shows evidence that depressive symptoms predicted some sexual risk. This implies that there should be upstream interventions to prevent depressive symptoms and associated risky sexual behaviours. Though some of the associations were different for women and men, treating depressive symptoms in both sexes could result in a reduction of risky sexual behaviours and relationships.
Youth mental health services remain neglected in sub-Saharan Africa. The Lancet Global Mental Health Group issued a "call for action" in 2007 to strengthen mental health services across the globe, particularly in low-income countries, and emphasized the prevalence and burden of depressive disorders and the low cost of effective interventions . Mental health investments could have an enormous impact on public health and specifically on the HIV epidemic in sub-Saharan Africa. We recommend that the existing youth-friendly sexual and reproductive health services, which are more widely available, accessible and already tackle health issues, such as teenage unplanned pregnancies and HIV prevention, should integrate prevention, diagnosis and management of depressive symptoms in youth.
Funding came from the National Institute of Mental Health grant Nos MH64882-01, MH64882-04S1A1, 1R03MH085599 and the South African Medical Research Council. MN is supported by the Carnegie Fellowship Award. IC is supported by a New Investigator award from the Canadian Institutes of Health Research and a Population Health Investigator award from the Alberta Heritage Foundation for Medical Research.
We thank all the members of the Stepping Stones Study team, the staff who worked on the project, members of the community advisory board and DSMB.
- Magnussen L, Ehiri JE, Ejere HO, Jolly PE: Interventions to prevent HIV/AIDS among adolescents in less developed countries: are they effective? International Journal of Adolescent Medicine and Health 2004, 16: 303–323.PubMedGoogle Scholar
- Karim AM, Williams T, Patykewich L, Ali D, Colvin CE, Posner Jessica, Rutaremwa Gideon: The Impact of the African Youth Alliance Program on the Sexual Behavior of Young People in Uganda. Studies in Family Planning 2009, 40: 289–306.View ArticleGoogle Scholar
- Karim QA, Karim SSA: The evolving HIV epidemic in South Africa. International Journal of Epidemiology 2002, 31: 37–40.View ArticleGoogle Scholar
- Shisana O, Rehle T, Simbayi L, Zuma K, Jooste S, Shisana O, Rehle T, Simbayi LC, Zuma K, Jooste S, Pillay-van Wyk V, Mbelle N, Van Zyl J, Parker W, Zungu NP, Pezi S, the SABSSM III Implementation Team: South African National HIV Prevalence, Behaviour and Communication Survey, 2008: A Turning Tide Among Teenagers?. Pretoria: Human Sciences Research Council Press; 2009.Google Scholar
- Green EC, Mah TL, Ruark A, Hearsy N: A framework for sexual relationships: risks and implications for HIV prevention in Africa. Studies in Family Planning 2009, 40: 63–70.View ArticlePubMedGoogle Scholar
- Fassin D: The embodied past. From paranoid style to politics of memory in South Africa. Social Anthropology 2008, 16: 312–328.View ArticleGoogle Scholar
- Parkhursta JO: Understanding the correlations between wealth, poverty and human immunodeficiency virus infection in African countries. Bulletin of the World Health Organization 2010, 88: 519–526.View ArticleGoogle Scholar
- Lancet Global Mental Health Group, Chisholm D, Flisher AJ, Lund C, Patel V, Saxena S, Thornicroft G, Tomlinson M: Scale up services for mental disorders: a call for action. The Lancet 2007, 370: 1241–1252.View ArticleGoogle Scholar
- Myer L, Stein DJ, Grimsrud A, Seedat S, Williams DR, Stein DJ: Social determinants of psychological distress in a nationally-representative sample of South African adults. Social Science & Medicine 2008, 66: 1828–1840.View ArticleGoogle Scholar
- Smit J, Myer L, Middelkoop K, Seedat S, Wood R, Bekker LG, Stein DJ: Mental health and sexual risk behaviours in a South African township: A community-based cross-sectional study. Journal of Royal Institute of Public Health 2006, 120: 534–542.Google Scholar
- Hamad R, Fernald LCH, Karlan DS, Zinman J: Social and economic correlates of depressive symptoms and perceived stress in South African adults. Journal of Epidemiology Community Health 2008, 62: 538–544.View ArticleGoogle Scholar
- Mkize LP, Nonkelela NF, Mkize DL: Prevalence of depression in a university population. Curationis 1998, 21: 32–37.PubMedGoogle Scholar
- Stiffman AR, Dore P, Cunningham RM, Earls F: Person and Environment in HIV Risk Behavior Change Between Adolescence and Young Adulthood. Health Education & Behavior 1995, 22: 211–226.View ArticleGoogle Scholar
- Mpofu E, Flisher AJ, Bility K, Onya H, Lombard C: Sexual Partners in a Rural South African Setting. AIDS & Behavior 2006, 10: 399–404.View ArticleGoogle Scholar
- Soul City: One Love. In Multiple and concurrent sexual partnerships in Southern Africa: A ten country research report. Johannesburg: Soul City Institute Regional Programme; 2008.Google Scholar
- Lehrer JA, Shrier LA, Gortmaker SL, Buka S: Depressive symptoms as a longitudinal predictor of sexual risk behaviours among US middle and high school students. Pediatrics 2006, 118: 189–200.View ArticlePubMedGoogle Scholar
- Bhana A, Petersen I: HIV and Youth: A Behavioural Perspective. In HIV/AIDS in South Africa 25 Years On. Edited by: Rohleder P, Swartz L, Kalichman SC, Simbayi LC. New York: Springer; 2009:55–68.View ArticleGoogle Scholar
- Rubin A, Gold M, Primack B: Associations between depressive symptoms and sexual risk behavior in a diverse sample of female adolescents. Journal of Pediatric and Adolescent Gynecology 2009, 22: 306–312.View ArticlePubMedGoogle Scholar
- Borowsky IW, Ireland M, Resnick MD: Health status and behavioral outcomes for youth who anticipate a high likelihood of early death. Pediatrics 2009, 124: e81-e88.View ArticlePubMedGoogle Scholar
- Keller SE, Bartlett JA, Schleifer SJ, Johnson RL, Pinner E, Dilaney B: HIV-relevant sexual behavior among a healthy inner-city heterosexual adolescent population in an endemic area of HIV. Journal of Adolescent Health 1991, 12: 44–48.View ArticlePubMedGoogle Scholar
- Kloep M, Guney N, Cok F, Simsek OF: Motives for risk-taking in adolescence: a cross-cultural study. Journal of Adolescence 2007, 13: 135–155.Google Scholar
- Paxton KC, Robison WL: Depressive symptoms, gender and sexual risk behaviour among African-American adolescents: Implications for prevention and intervention. Journal of Prevention and Intervention in Community 2008, 35: 49–62.View ArticleGoogle Scholar
- Mazzaferro KE, Murray PJ, Ness RB, Bass DC, Tyus N, Cook R L: Depression, Stress, and Social Support as Predictors of High-Risk Sexual Behaviors and STIs in Young Women. Journal of Adolescent Health 2006, 39: 601–603.View ArticlePubMedGoogle Scholar
- Kosunen E, Kaltiala-Heino R, Rimpela M, Laippala P: Risk-taking sexual behaviour and self-reported depression in middle adolescence - a school-based survey. Child Care, Health and Development 2003, 29: 337–344.View ArticlePubMedGoogle Scholar
- Peltzer K: Stress, psychological symptoms, social support and health behaviour among black students in South Africa. Journal of Child and Adolescent Mental Health 2004, 16: 19–23.View ArticleGoogle Scholar
- Ramrakha S, Caspi A, Dickson N, Moffit TE, Paul C: Psychiatric disorders and risky sexual behaviours in young adulthood: cross sectional study in birth cohort. British Medical Journal 2000, 321: 263–266.View ArticlePubMedGoogle Scholar
- Seth P, Raiji PT, DiClemente RJ, Wingood GM, Rose E: Psychological distress as a correlate of a biologically confirmed STI, risky sexual practice, self-efficacy and communication with male sex partners in African-American female adolescents. Psychology, Health and Medicine 2009, 14: 291–300.View ArticleGoogle Scholar
- DiClemente RJ, Wingood GM, Crosby RA, Sionean C, Brown LK, Rothbaum B, Zimand E, Cobb BK, Harrington K, Davies S: A Prospective Study of Psychological Distress and Sexual Risk Behavior Among Black Adolescent Females. Pediatrics 2001, 108: E85.View ArticlePubMedGoogle Scholar
- Jewkes R, Nduna M, Levin J, Jama N, Dunkle K, Khuzwayo N, Koss M, Puren A, Wood K, Duvvury N: A cluster randomized-controlled trial to determine the effectiveness of Stepping Stones in preventing HIV infections and promoting safer sexual behaviour amongst youth in the rural Eastern Cape, South Africa: trial design, methods and baseline findings. Tropical Medicine & International Health 2006, 11: 3–16.View ArticleGoogle Scholar
- Jewkes R, Nduna M, Levin J, Jama N, Dunkle K, Puren A, Duvvury N: Impact of Stepping Stones on incidence of HIV and HSV-2 and sexual behaviour in rural South Africa: cluster randomised controlled trial. British Medical Journal 2008, 337: a506.View ArticlePubMedGoogle Scholar
- Allen JP, Reinert DF, Volk R: The Alcohol Use Disorders Identification Test: An Aid to Recognition of Alcohol Problems in Primary Care Patients. Preventive Medicine 2001, 33: 428–433.View ArticlePubMedGoogle Scholar
- Bernstein DP, Stein JA, Newcomb MD, Walker E, Pogge D: Development and validation of a brief screening version of the Childhood Trauma Questionnaire. Child Abuse & Neglect 2003, 27: 169–190.View ArticleGoogle Scholar
- Jewkes R, Dunkle KL, Nduna M, Jama N, Puren A: Associations between childhood adversity and depression, substance abuse & HIV & HSV2 incident infections in rural South African youth. Child Abuse & Neglect 2010, in press.Google Scholar
- Radloff LS: The CES-D Scale: A self-report depression scale for research in the general population. Applied Psychological Measurement 1977, 1: 385–401.View ArticleGoogle Scholar
- Myers J, Weissman M: Use of a self-report symptom scale to detect depression in a community sample. American Journal of Psychiatry 1980, 137: 1081–1084.PubMedGoogle Scholar
- Jewkes R, Dunkle K, Nduna M, Levin J, Jama N, Khuzwayo M, Koss M, Puren A, Duvvury N: Factors associated with HIV sero-status in young rural South African women: connections between intimate partner violence and HIV. International Journal of Epidemiology 2006, 35: 1461–1468.View ArticlePubMedGoogle Scholar
- Dunkle KLJRK, Brown HC, Gray GE, McIntryre JA, Harlow SD: Gender-based violence, relationship power, and risk of HIV infection in women attending antenatal clinics in South Africa. Lancet 2004, 363: 1415–1421.View ArticlePubMedGoogle Scholar
- Pulerwitz J, Gortmaker SL, DeJong W: Measuring Sexual Relationship Power in HIV/STD Research. Sex Roles 2000, 42: 637–660.View ArticleGoogle Scholar
- World Health Organization: WHO Multi-country study on Women's health and Domestic Violence: Core questionnaire and WHO Instrument - Version 9. Geneva, Switzerland: World Health Organization; 2000.Google Scholar
- Fernander AG, Flischer AJ, King G, Noubary FM, Lombard C, Price M, Chalton D: Gender differences in depression and smoking among youth in Cape Town, South Africa. Ethnicity and Disease 2006, 16: 41–50.PubMedGoogle Scholar
- Speizer IS, Pettifor A, Cummings S, MacPhail C, Kleinschmidt I, Rees HV: Sexual Violence and Reproductive Health Outcomes Among South African Female Youths: A Contextual Analysis. American Journal of Public Health 2009, 99: S425–431.View ArticlePubMedGoogle Scholar
- Maharaj P, Munthree C: Coerced first sexual intercourse and selected reproductive health outcomes among young women in KwaZulu-Natal, South Africa. Journal of Biosocial Science 2007, 39: 231–244.View ArticlePubMedGoogle Scholar
- Potard C, Courtois R, Rusch E: The influence of peers on risky sexual behaviour during adolescence. The European Journal of Contraception and Reproductive Health Care 2008, 13: 264–270.View ArticleGoogle Scholar
- DiClemente RJ, Crittenden CP, Rose E, Sales JM, Wingood GM, Crosby RA, Salazar LF: Psychosocial Predictors of HIV-Associated Sexual Behaviors and the Efficacy of Prevention Interventions in Adolescents at-Risk for HIV Infection: What Works and What Doesn't Work? Psychosomatic Medicine 2008, 70: 598–605.View ArticlePubMedGoogle Scholar
- Brook DW, Morojele NK, Zhang C, Brook : South African Adolescents: Pathways to Risky Sexual Behavior. AIDS Education and Prevention 2006, 18: 259–272.View ArticlePubMedGoogle Scholar
- Anderson KL: Perpetrator or Victim? Relationships between Intimate Partner Violence and Well-Being. Journal of Marriage and Family 2002, 64: 851–863.View ArticleGoogle Scholar
- Bonomi AE, Thompson RS, Anderson M, Reid R, Carrell D, Dimer JA, Rivara FP: Intimate Partner Violence and Women's Physical, Mental, and Social Functioning. American Journal of Preventive Medicine 2006, 30: 458–466.View ArticlePubMedGoogle Scholar
- Goodman L, Fallot R: HIV risk-behavior in poor urban women with serious mental disorders: association with childhood physical and sexual abuse. American Journal of Orthopsychiatry 1998, 68: 73–83.View ArticlePubMedGoogle Scholar
- Paul JP, Catania J, Pollack L, Stall : Understanding childhood sexual abuse as a predictor of sexual risk-taking among men who have sex with men: The Urban Men's Health Study. Child Abuse & Neglect 2001, 25: 557–584.View ArticleGoogle Scholar
- Bensley LS, Van Eenwyk J, Simmons KW: Self-reported childhood sexual and physical abuse and adult HIV-risk behaviors and heavy drinking. American Journal of Preventive Medicine 2000, 18: 151–158.View ArticlePubMedGoogle Scholar
- Dunkle KL, Jewkes RK, Nduna M, Levin J, Jama N, Khuzwayo M, Koss M, Duvvury N: Perpetration of partner violence and HIV risk behaviour among young men in the rural Eastern Cape, South Africa. AIDS 2006, 20: 2107–2114.View ArticlePubMedGoogle Scholar
- Makiwane M, Kwizera S: Youth and Well-Being: A South African Case Study. Social Indicators Research 2008, 91: 223–242.View ArticleGoogle Scholar
- UNAIDS/WHO: [http://data.unaids.org/pub/FactSheet/2009/20091124_fs_ssa_en.pdf] Uniting the world against AIDS. FACT SHEET 09. Sub-Saharan Africa: Latest epidemiological trends.
- Kasenda M, Calzavara LM, Johnson I, LeBlanc : Correlates of condom use in the young adult population in Ontario. Canadian Journal of Public Health 1997, 88: 280–285.Google Scholar
- Shai NJ, Jewkes R, Nduna M, Levin J, Dunkle K: Factors associated with consistent condom use among rural young women in South Africa. AIDS Care 2010, 22: 1379–1385.View ArticleGoogle Scholar
- Jewkes R: HIV and Women. In HIV/AIDS in South Africa 25 Years On. Edited by: Rohleder P, Swartz L, Kalichman SC, Simbayi LC. Springer New York; 2009:27–40.View ArticleGoogle Scholar
- Chapman R, White RG, Shafer LA, Pettifor A, Mugurungi O, Ross D, Oascoe S, Cowan FM, Grosskurth H, Buve A, Hayes RJ: Do behavioural differences help to explain variations in HIV prevalence in adolescents in sub-Saharan Africa? Tropical Medicine & International Health 2010, 15: 554–566.View ArticleGoogle Scholar
- Patel V, Araya R, de Lima M, Ludermir A, Todd C: Women, poverty and common mental disorders in four restructuring societies. Social Science & Medicine 1999, 49: 1461–1471.View ArticleGoogle Scholar
- Dunkle KL, Jewkes R, Nduna M, Jama N, Levin J, Sikweyiya Y, Koss MP: Transactional sex with casual and main partners among young South African men in the rural Eastern Cape: Prevalence, predictors, and associations with gender-based violence. Social Science & Medicine 2004, 65: 1235–1248.View ArticleGoogle Scholar
- Jewkes R, Dunkle K, Nduna M, Jama Shai N: Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet 2010, 376 (9734) : 41–48.View ArticlePubMedGoogle Scholar
- Mitchell K, Wellings K, Elam G, Erens B, Fenton K: How can we facilitate reliable reporting in surveys of sexual behaviour? Evidence from qualitative research. Culture, Health & Sexuality 2007, 9: 519–531.View ArticleGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.