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Table 1 Comparison of acute and established HIV infections in British Columbia (N = 987)

From: Towards targeted screening for acute HIV infections in British Columbia

Characteristic

Acute cases

N = 61

Established cases

N = 926

P value

Unadjusted OR

Mean age (Range)

38.6 (20-75 yr)

39.1 (0-81 yr)

0.75

-

Sex

Male

52/61 (85.2%)

735/922 (79.7%)

0.295

1.47 [0.71, 3.04]

Ethnicity

Caucasian

43/60 (71.7%)

540/853 (63.3%)

0.193

1.47 [0.82,2.61]

 

Aboriginal

9/60 (15.0%)

130/853 (15.2%)

0.960

0.98 [0.47, 2.04]

 

Other

8/60 (13.3%)

183/853 (21.5%)

0.135

0.56 [0.26, 1.21]

MSM

36/61 (59.0%)

424/926 (45.8%)

0.045

1.71 [1.01, 2.89]

IDU

15/61 (24.6%)

266/926 (28.7%)

0.488

0.81 [0.44, 1.47]

Heterosexual

12/61 (19.7%)

195/926 (21.1%)

0.797

0.92 [0.48, 1.76]

Reason for testing due to seroconversion symptoms

20/61 (32.8%)

80/926 (8.6%)

0.000

5.16 [2.88, 9.23]

Documented previous negative HIV test

49/61 (80.3%)

542/926 (58.5%)

0.001

2.89 [1.52, 5.51]

HIV subtype

A1

0/49 (0.0%)

6/686 (0.9%)

-

-

 

B

47/49 (95.9%)

633/686 (92.3%)

0.574

1.97 [0.51, 7.52]

 

C

0/49 (0.0%)

22/686 (3.2%)

-

-

 

CRF 01_AE

2/49 (4.1%)

11/686 (1.6%)

0.201

2.61 [0.63, 10.87]

 

Other

0/49 (0.0%)

10/686 (1.5%)

-

-

Drug Resistance Class

Wild type

45/49 (91.8%)

611/684 (89.3%)

0.809

1.34 [0.49, 3.69]

 

NRTI

2/49 (4.1%)

25/684 (3.7%)

0.878

1.12 [0.29, 4.42]

 

NNRTI

2/49 (4.1%)

28/684 (4.1%)

0.997

1.01 [0.26, 3.91]

 

PI

1/49 (2.0%)

18/684 (2.6%)

0.802

0.77 [0.13, 4.65]

 

MDRa

1/49 (2.0%)

2/684 (0.3%)

0.064

7.10 [0.92, 55.44]

  1. a. These are included in the totals for each class.
  2. Abbreviations: IDU - injection drug user; MDR - multi-drug resistant; MSM - men who have sex with men; NNRTI - non-nucleoside reverse transcriptase inhibitor; NRTI - nucleoside reverse transcriptase inhibitor; PI - protease inhibitor