# ARV regimens | Monitoring strategy | Freq-uency (mo.) | Viral load thres-hold | 5-year outcomes | Cost, $2008 | QALY | ICER, $/QALY | Value com-pared with earlier treatment initiation* | |||
---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  |  | Mean # ARV rounds used | Mean new mut-ations | Median CD4 (cells/mm 3 ) | Median HIV (log units) |  |  |  |  |
0 | Nothing | NA | NA | 0 | 0 | 0 | 0 | 807 | 1.966 | NA | NA |
1 | Clinical | 3 | NA | 1 | 1.05 | 265 | 2.79 | 5713 | 9.901 | 600 | Better |
2 | Viral load only if CD4 meets WHO criteria†‡ | 12 | 10,000 | 1.23 | 1.09 | 270 | 2.7 | 11,691 | 10.890 | 6000 | Worse |
2 | Viral load only if CD4 meets WHO criteria†¶ | 12 | 500 | 1.27 | 1.06 | 270 | 2.66 | 12,060 | 10.948 | 6400 | Worse |
2 | Viral load | 12 | 10,000 | 1.33 | 1.02 | 277 | 2.69 | 13,308 | 11.125 | 7100 | Worse |
2 | Viral load§ | 12 | 500 | 1.67 | 0.82 | 285 | 2.42 | 16,035 | 11.412 | 9500 | Worse |
3 | Viral load | 12 | 10,000 | 1.45 | 1.03 | 280 | 2.68 | 19,900 | 11.652 | 16,100 | Worse |
3 | Viral load | 12 | 500 | 2.06 | 0.81 | 290 | 2.38 | 25,527 | 11.941 | 19,500 | Worse |
3 | Viral load | 6 | 500 | 2.12 | 0.77 | 290 | 2.36 | 26,927 | 11.988 | 29,800 | Worse |
3 | Viral load | 3 | 500 | 2.16 | 0.76 | 290 | 2.34 | 29,063 | 12.018 | 71,200 | Worse |