Table 1 Comparisons of the enrolment characteristics of the analysis cohort by creatinine clearance and estimated glomerular filtration rate categories
Creatinine clearance (mL/min)a Glomerular filtration rateb (mL/min/1.73 m2)b | |||||||
|---|---|---|---|---|---|---|---|
Characteristic c | Total (n = 7383) | ≥60 (n = 5890; 79.8%) | < 60 (n = 1493; 20.2%) | P value | ≥60 (n = 6689; 90.6%) | < 60 (n = 694; 9.4%) | P value |
Age, years | 35.5 | 34.3 | 41.8 | < 0.001 | 35.1 | 39.0 | < 0.001 |
(29.3-44.0) | (28.7-41.0) | (33.8-49.4) | (29.1-42.6) | (32.1-46.5) | |||
Female, n (%) | 5399 (73.1) | 4289 (72.8) | 1110 (74.4) | 0.24 | 4851 (72.5) | 548 (79.0) | < 0.001 |
CD4 cell count/mm3, n (%) | |||||||
>500 | 2263 (30.7) | 1906 (32.4) | 357 (23.9) | < 0.001 | 2075 (31.0) | 188 (27.1) | 0.005 |
350-500 | 1993 (27.0) | 1605 (27.2) | 388 (26.0) | 1821 (27.2) | 172 (24.8) | ||
< 350 | 3127 (42.4) | 2379 (40.4) | 748 (50.1) | 2793 (41.8) | 334 (48.1) | ||
WHO stage 1, n (%) | 5019 (68.0) | 4054 (68.8) | 965 (64.6) | 0.002 | 4528 (67.7) | 491 (70.8) | 0.10 |
Haemoglobin, g/dL | 12.6 | 12.6 | 12.2 | < 0.001 | 12.6 | 12.3 | 0.003 |
(10.9-14.0) | (11.0-14.0) | (10.6-13.7) | (11.0-14.0) | (10.6-13.8) | |||
Weight, kg | 59.0 | 60.0 | 53.4 | < 0.001 | 59.0 | 59.8 | 0.04 |
(52.0-65.5) | (54.0-67.0) | (48.0-60.0) | (52.0-65.5) | (53.0-67.0) | |||
Serum creatinine, mg/dL | 0.8 | 0.77 | 1.1 | < 0.001 | 0.80 | 1.4 | < 0.001 |
(0.7-1.0) | (0.66-0.90) | (1.0-1.3) | (0.68-0.93) | (1.2-1.6) | |||