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Table 2 Confirmed Virologic Response (CVR) VL<50 at Wk 48 (ITT) by Baseline Substitutions.

From: Impact of HIV viral diversity and baseline resistance on treatment outcomes and the emergence of resistance: the CASTLE study 48-week results

 

ATV/r n/N (%)

LPV/r n/N (%)

PI-IAS-USA Major/Minor 0

224/290 (77)

202/257 (79)

PI-IAS-USA Major/Minor 1–2

110/138 (80)

128/170 (75)

PI-IAS-USA Major/Minor ≥ 3

3/3 (100)

1/2 (50)

PI Polymorphisms ≥ 5

191/251 (76)

173/222 (78)

NRTI (any IAS or Stanford) ≥ 1

57/73 (78)

51/64 (80)

  1. * Estimated difference: 1.7 (95% CI, -3.8%, 7.1%). 18 reported HIV subtypes contain 6 subtypes, 3 sub-subtypes and 9 recombinants.
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Journal of the International AIDS Society

ISSN: 1758-2652