Table 1 Measurements are mean (+/- SD). RNA expressions are in arbitrary units. * control vs. HIV naïve, ** control vs. HIV 6 mth *** HIV naïve vs. HIV 6 mth.
| Â | Control | HIV Naive | HIV AZT 6 m | HIV TDF 6 m | p all HIV 6 m |
|---|---|---|---|---|---|
Adiponectin ug/ml | 8.2 (4.9) | 10.3 (4.1) | 13.3 (6.8) **p = 0.025, ***p = 0.05 | 9.4 (3.3) | **0.04, ***0.01 |
Hepatic lipase nmol/ml/h | 200 (119) | 126 (80) | 148 (110) | 137 (93) | NS |
LPL nmol/ml/h | 528 (151) | 297 (107) *p = 0.0001 | 382 (212) **p = 0.05, ***p = 0.05 | 341 (167) **p = 0.12 | **0.008 |
LPL mRNA | 173 (106) | 188 (97) | 187 (68) **p = 0.05 | 167 (114) **NS | **0.004, ***0.007 |
HSL mRNA | 0.38 (0.29) | 0.38 (0.29) | 1.2 (1.5) **p = 0.05, ***p = 0.05 | 1.3 (1.6) **p = 0.02, ***p = 0.015 | **0.02, ***0.001 |
Adiponectin mRNA | 30.9 (25.4) | 26.1 (9.1) | 39.4 (20.1) ***p = 0.09(NS) | 33.2 (10.8) ***p = NS | NS |