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Table 1 PI and NRTI Resistance Mutations Observed Between Weeks 24 and 108 in Patients Experiencing Virologic Failure in the M98-863 Study[2]

From: Genetic Barriers to Resistance and Impact on Clinical Response

Regimen PI resistance 3TC resistance d4T resistance
LPV/r + d4T + 3TC(N = 326) 0/51 (0%) 19/51 (37%) 0/50 (0%)*
NFV + d4T + 3TC(N = 327) 43/96 (45%) 79/96 (82%) 9/96 (9%)
  1. * There was evidence of archival resistance at codon 215 in one patient who was disqualified from the analysis.