Skip to main content

Table 1 PI and NRTI Resistance Mutations Observed Between Weeks 24 and 108 in Patients Experiencing Virologic Failure in the M98-863 Study[2]

From: Genetic Barriers to Resistance and Impact on Clinical Response

Regimen

PI resistance

3TC resistance

d4T resistance

LPV/r + d4T + 3TC(N = 326)

0/51 (0%)

19/51 (37%)

0/50 (0%)*

NFV + d4T + 3TC(N = 327)

43/96 (45%)

79/96 (82%)

9/96 (9%)

  1. * There was evidence of archival resistance at codon 215 in one patient who was disqualified from the analysis.