High Prevalence of Hepatitis B Virus Markers in Romanian Adolescents With Human Immunodeficiency Virus Infection

Table 3 Influence of the Degree of Immunosuppression on HBV Serologic Markers

HBV Markers	HIV Patients With CD4+ Cell Counts > 200 cells/mcL (n = 104)	HIV Patients With CD4+ Cell Counts < 200 cells/mcL (n = 57)	P *
Anti-HBc	77 (74.1%)	49 (85.9%)	.11
HBsAg	38 (34.6%)	32 (59.6%)	.02
HBeAg	8 (7.7%)	10 (17.5%)	.06
HBV DNA (>10⁷ copies/mL)	6 (5.7%)	13 (22.8%)	.002
Anti-HBs	15 (14.4%)	8 (14%)	1
Without HBV markers	27 (25.9%)	8 (14.1%)	.11

* Differences, calculated by Fisher's exact test, were considered to be statistically significant at 2-tailed P values <.05
NS = non significant; NA = not applicable