Failure to prescribe pneumocystis prophylaxis is associated with increased mortality, even in the cART era: results from the Treat Asia HIV observational database

Table 2 Predictors of mortality

	Number of patients*	Death	Person times (year)	Rate (per 100 person-years)	adjusted IRR**	95% CI	p value
Receiving PCP prophylaxis
Yes	1567	29	2498.98	1.16	1.00
No	3439	140	9942.75	1.41	10.83	(6.258, 18.744)	< 0.001
Age group
Age < 40	2585	80	6650.09	1.20	1.00
Age 40+	2011	89	5791.64	1.54	1.96	(1.287, 2.997)	0.002
CD4 count (cells/mm ³ )
< = 49	442	57	337.69	16.88	1.00
50~99	513	18	366.94	4.91	0.20	(0.100, 0.400)	< 0.001
100~199	1352	32	1446.18	2.21	0.08	(0.043, 0.141)	< 0.001
200~299	1856	26	2130.43	1.22	0.03	(0.013, 0.049)	< 0.001
300+	3042	29	8088.58	0.36	0.01	(0.003, 0.012)	< 0.001
Not available	120	7	71.91	9.73	0.13	(0.044, 0.384)	< 0.001
CDC stage
Stage A	1889	42	5266.13	0.80	1.00
Stage B	474	14	1459.02	0.96	1.56	(0.723, 3.355)	0.257
Stage C	1895	113	5716.58	1.98	2.36	(1.423, 3.903)	0.001
Antiretroviral treatment
No ART	843	30	1331.76	2.25	1.00
Mono/double	96	4	152.1	2.63	0.99	(0.257, 3.792)	0.984
HAART	3597	135	10957.87	1.23	0.38	(0.219, 0.647)	< 0.001