Table 1 Baseline characteristics of HIV-infected adults admitted to Bugando Medical Centre divided by diagnosis
| Â | Cryptococcal meningitis (n = 15) | Other diagnoses (n = 318) | p value |
|---|---|---|---|
Age (years) | Â | Â | Â |
   18-30 | 3 (20.0%) | 85 (26.7%) | 0.77 |
   31-40 | 4 (26.7%) | 118 (37.1%) | 0.59 |
   41-50 | 5 (33.3%) | 70 (22.01%) | 0.34 |
   51-60 | 2 (13.3%) | 30 (9.4%) | 0.65 |
   > 60 | 1 (6.7%) | 15 (4.7%) | 0.53 |
   Median (IQR) | 41.0 (32-47) | 36.0 (30-44) | 0.29 |
Gender | Â | Â | Â |
   Male | 7 (46.7%) | 147 (46.2%) | 1 |
   Female | 8 (53.3%) | 171 (53.8%) |  |
CD4 profile (cells/mm 3 ) | Â | Â | Â |
   < 100 | 14 (93.3%) | 79 (24.8%) | < 0.0001 |
   100-200 | 1 (6.7%) | 61 (19.2%) | 0.32 |
   > 200 | 0 (0%) | 178 (56.0%) | < 0.0001 |
   Median (IQR) | 68.0 (54-87) | 228.0 (101-379) | 0.0006 |
HIV status on admission | Â | Â | Â |
   New diagnosis | 6(40%) | 84(26.42%) | 0.25 |
   Known | 9(60%) | 234(73.58%) |  |
Days on antiretroviral therapy | Â | Â | Â |
   Never | 8 (53.3%) | 162 (50.9%) | 1 |
   < 180 | 5 (33.3%) | 43 (13.5%) | 0.05 |
   > 180 | 2 (13.3%) | 113 (35.5%) | 0.097 |
   Median (IQR) | 92 (61-214) | 293 (147-589) | 0.003 |
Symptoms/signs on admission | Â | Â | Â |
   Headache | 11 (73.3%) | 87 (27.6%) | 0.0004 |
   Fever (T > 37.5°C) | 14 (93.3%) | 204 (64.2%) | 0.02 |
   Altered mental status (GCS ≤14) | 10 (66.7%) | 19 (6.0%) | < 0.0001 |
   Neck stiffness | 9 (60%) | 22 (6.9%) | 0.0001 |
   None of the above | 0 | 97 (30.5%) |  |
   ≥ 1 of the above | 15 (100%) | 221 (69.5%) | 0.007 |
   ≥ 2 of the above | 15 (100%) | 108 (33.9%) | < 0.0001 |