Retention in an antiretroviral therapy programme during an era of decreasing drug cost in Limbe, Cameroon

Mosoko, Jembia J; Akam, Wilfred; Weidle, Paul J; Brooks, John T; Aweh, Asabi J; Kinge, Thompson N; Pals, Sherri; Raghunathan, Pratima L

doi:10.1186/1758-2652-14-32

Journal of the International AIDS Society

Table 4 Factors associated with dropping out of care immediately after initiating ART in the Limbe ART programme, Feb 2002-Dec 2005

From: Retention in an antiretroviral therapy programme during an era of decreasing drug cost in Limbe, Cameroon

		Complete Cases				Multiple Imputation
Characteristic	n/N	%	Crude HR	Adjusted HR	Missing N(%)	Crude HR	Adjusted HR
			(95% CI)	(95% CI)		(95% CI)	(95% CI)
Age group
30+	441/2081	21.2	1.00	1.00	116	1.00	1.00
< 30	159/723	22.0	1.06 (0.83, 1.33)	1.07 (0.82, 1.40)	(3.97)	1.03 (0.84, 1.27)	1.09 (0.86, 1.37)
Sex*
Male	215/1104	19.5	1.00	1.00	1	1.00	1.00
Female	416/1815	22.9	1.20 (0.77, 1.49)	1.24 (0.98, 1.57)	(0.03)	1.23 (1.02, 1.49)	1.22 (1.00, 1.50)
Occupation*
Unemployed	137/706	19.4	1.00	1.00	170	1.00	1.00
With some kind of income	453/2044	22.2	1.12 (0.88, 1.43)	1.23 (0.95, 1.60)	(5.82)	1.19 (0.96, 1. 49)	1.27 (1.00, 1.61)
Marital status*
Married/ living as	232/1166	19.9	1.00	1.00	143	1.00	1.00
Never	266/1207	22.0	1.07 (0.86, 1.35)	1.01 (0.79, 1.28)	(4.90)	1.14 (0.94, 1.39)	1.03 (0.84, 1.27)
Previous marriage	97/404	24.0	1.13 (0.82, 1.54)	1.05 (0.76, 1.46)		1.28 (0.97, 1.68)	1.16 (0.87, 1.54)
Residence by distance to ART clinic*
Residents in Limbe	138/621	22.2	1.00	1.00	117	1.00	1.00
Residents < 40 km from Limbe	177/801	22.1	1.16 (0.87, 1.55)	1.16 (0.86, 1.57)	(4.01)	1.01 (0.79, 1.29)	0.95 (0.74, 1.22)
Residents 40-150 km from Limbe	156/788	19.8	0.84 (0.62, 1.15)	0.82 (0.60, 1.13)		0.87 (0.68, 1.13)	0.83 (0.64, 1.08)
Residents > 150 km from Limbe	97/454	21.4	1.06 (0.75, 1.50)	1.04 (0.74, 1.48)		0.95 (0.71, 1.28)	0.92 (0.69, 1.23)
Residents from Douala, 74 km away***	31/139	22.3	0.97 (0.57, 1.64)	1.00 (0.59, 1.69)		1.01 (0.65, 1.56)	0.95 (0.61, 1.47)
Means of payment for antiretroviral drugs*
Entirely paid by programme or employer	14/87	16.1	1.00	1.00	592	1.00	1.00
Paid by self, family or partly by other	456/2241	20.4	0.86 (0.46, 1.61)	0.80 (0.42, 1.52)	(20.27)	1.33 (0.74, 2.39)	1.25 (0.67, 2.32)
Cohort
Enrolled before Oct 1,2004	295/1487	19.8	1.00	1.00	0	N/A	1.00
Enrolled on or after Oct 1,2004	336/1433	23.5	1.06 (0.86, 1.30)	1.05 (0.85, 1.30)	(0.0)		1.22 (1.03, 1.46)
Entry CD4 count (cells/μL)
> 100	296/1428	20.7	1.00	1.00	205	1.00	1.00
0-99	292/1287	22.7	1.09 (0.88, 1.34)	1.08 (0.87, 1.33)	(7.02)	1.13 (0.94, 1.35)	1.14 (0.95, 1.36)

(Complete case N = 2188; Multiple Imputation N = 2920).
*Sample size smaller due to missing values, **Difficult access took into account the distance from ART centre as well as the presence of unpaved or poorly maintained road, ***Patients residing in Douala with regular transport on paved roads and may have had other ART opportunities. Abbreviations: ART (antiretroviral therapy)

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