Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia

Table 3 Time-dependent predictors of mortality and loss to follow up at 90 days, adjusted for baseline biomarker value

Serum biomarker	Adjusted HR mortality (95% CI)^a	p-value	Adjusted HR mortality or loss to follow up (95% CI)	p-value
Phosphate (per 0.1 mmol/L increase)	0.90 (0.77, 1.05)	0.178	0.97 (0.87, 1.07)	0.529
Albumin (per 5 g/L increase)	0.62 (0.43, 0.89)	0.010	0.70 (0.56, 0.87)	0.002
Ferritin (per 100 μg/L increase)	1.05 (0.89, 1.24)	0.536	1.05 (0.93, 1.19)	0.428
hsCRP (per 5 mg/L increase)	1.25 (0.74, 2.12)	0.390	1.33 (0.87, 2.03)	0.184

^a Models adjusted for the baseline value of each biomarker, sex, and a first principal component (incorporating age, body mass index, CD4+ lymphocyte count, and hemoglobin).
Abbreviation: hsCRP, highly sensitivite C-reactive protein.
Note: Participants with no lab values were dropped from the Cox models, and time intervals with no corresponding serum level are excluded from analysis.