Table 2 Characteristics of the patients diagnosed with a non-AIDS-defining malignancy compared with the cohort.
From: Characteristics of non-AIDS-defining malignancies in the HAART era: a clinico-epidemiological study
Cohort | NADM | No NADM | Univariate | Multivariate | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | p value | OR | CI 95% | p value | OR | CI 95% | |
Patients | 3126 | 100 | 45 | 1.4 | 3081 | 98.6 | ||||||
Included after 1 January 2002 | 1300 | 41.6 | 10 | 22.2 | 1290 | 41.9 | ||||||
Median follow up | 49 | 60 | 49 | |||||||||
Age > 45 at baseline | 703 | 22.49 | 24 | 53.33 | 679 | 22.04 | < 0.0001 | 4.04 | 2.24-7.31 | < 0.0001 | 3.25 | 1.70-6.22 |
Smoking | 984 | 31.5 | 19 | 42.2 | 965 | 31.3 | 0.1611 | |||||
MSM | 875 | 28.0 | 11 | 24.4 | 864 | 28.0 | 0.714 | |||||
Male | 1791 | 57.3 | 30 | 66.7 | 1761 | 57.2 | 0.2004 | |||||
African origin | 1582 | 50.6 | 19 | 42.2 | 1563 | 50.7 | 0.3255 | |||||
HCV | 319 | 10.2 | 10 | 22.2 | 309 | 10.0 | 0.0149 | 2.56 | 1.3 - 5.2 | 0.057 | 2.10 | 0.98-4.53 |
HBV | 192 | 6.1 | 4 | 8.5 | 188 | 6.1 | 0.6453 | |||||
HIV diagnosis >5 years | 1154 | 36.9 | 21 | 46.67 | 1133 | 36.77 | 0.1722 | |||||
Nadir CD4 count (cells/mm3) | 220 | 110 | 224 | |||||||||
Nadir CD4 count < 200/mm3 before 1 January 2002 | 1410 | 45.10 | 35 | 77.78 | 1375 | 44.63 | < 0.0001 | 4.34 | 2.14-8.80 | 0.005 | 3.10 | 1.40-6.87 |
CD4 count at baseline (cells/mm3) | 402 | 375.5 | 405 | 0.2782 | ||||||||
VL at baseline | 559 | 326 | 573 | 0.6767 | ||||||||
HAART use at baseline | 78.0 | 71.4 | 78.1 | 0.7514 | ||||||||
Cumulative duration of HAART | 39 | 50 | 38 | 0.1201 | ||||||||
Time since initiation of HAART | 45 | 55 | 44 | 0.0279 | ||||||||
AIDS events before inclusion | 635 | 20.31 | 15 | 33.3 | 620 | 20.12 | 0.0455 | 1.98 | 1.1 - 3.7 | 0.28 | 1.47 | 0.73-2.96 |
Death during study period | 146 | 4.67 | 20 | 44.4 | 126 | 4.1 | < 0.0001 | 18.76 | 10.1 - 34.7 | |||