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Table 1

From: Immune impairment and adaptive response in relation to antiretroviral therapy of HIV-infection

 

CD3+ (cells/mm3)

CD4+ (cells/mm3)

CD8+ (cells/mm3)

Viral Load (HIV) (log 10 copies/ml)

CD3+ CD4-CD8- (cells/mm3)

Late Presenters First Group

225

38

289

5,47

19

Late Presenters Second Group

552

26

380

6,09

179

HIV Living Cohort

2363

589

1195

3,80

394

  1. Though both groups had pronounced CD4 loss and high burden of the viral load, the amount of CD8+ and CD3+CD4-CD8- depletion was different between the groups and more profound in the first group compared with the second. For the first group with severe breakage of immunity combination regiments of HAART with boosted protease inhibitors, fusion and/or integration inhibitors are recommended even in the first line of therapy to obtain better results.