Skip to main content

Table 1 % patients with HIV-1 RNA <50 copies/mL at Week 48

From: Influence of demographic and disease parameters on virological response to once- vs twice-daily darunavir/ritonavir (DRV/r) at week 48 in ODIN

 

DRV/r qd

 

DRV/r bid

  

Baseline factor

N

% response

N

% response

Difference in response (95% CI)

HIV-1 RNA (as stratified) (copies/mL)

     

≤50,000

222

78.4

224

76.8

1.6 (-6.2, 9.4)

>50,000

72

52.8

72

52.8

0.0 (-16.4, 16.4)

CD4 count (cells/mm 3 )

     

<50

13

53.8

3

100

-46.2 (-109.6, 17.3)

50-<100

36

58.3

35

57.1

1.2 (-22.2, 24.6)

100-<200

76

77.6

77

67.5

10.1 (-4.1, 24.3)

200-<350

108

72.2

107

74.8

-2.5 (-14.4, 9.3)

≥350

61

77.0

74

74.3

2.7 (-12.0, 17.4)

Gender

     

Female

115

69.6

98

69.4

0.2 (-12.3, 12.7)

Male

179

73.7

198

71.7

2.0 (-7.0, 11.1)

Age (years)

     

≤30

35

71.4

35

60.0

11.4 (-11.0, 33.9)

30-≤45

180

75.6

169

72.8

2.8 (-6.4, 12)

45-≤55

64

60.9

72

72.2

-11.3 (-27.2, 4.6)

55-≤65

14

78.6

18

66.7

11.9 (-20.6, 44.4)

>65

1

100

2

100

0 (0, 0)

Race

     

Black

83

62.7

72

65.3

-2.6 (-17.9, 12.7)

Caucasian

102

71.6

110

69.1

2.5 (-9.9, 14.9)

Hispanic

47

72.3

59

67.8

4.5 (-13.2, 22.3)

Asian

48

89.6

41

87.8

1.8 (-11.6, 15.1)

Other

14

71.4

14

78.6

-7.1 (-40.7, 26.4)

Clade

     

B

179

70.4

199

64.3

6.4 (-3.4, 15.6)

Non-B

115

74.8

97

84.5

-9.8 (-20.7,1.2)