Table 1
PK parameter | 400/100 BID | 200/150 BID | 200/50 BID |
|---|---|---|---|
| Â | regimen 1 | regimen 2 | regimen 3 |
Lopinavir | Â | Â | Â |
AUC0-12 (ng.h/mL) | 99599 (87180-113787) | 73603 (65121-83191) | 45146 (39251-51927) |
Cmax (ng/mL) | 11965 (10400-13766) | 8939 (8047-9930) | 6404 (5648-7262) |
C12h (ng/mL) | 5776 (4884-6831) | 4293 (3603-5115) | 1749 (1419-2156) |
Ritonavir | Â | Â | Â |
AUC0-12 (ng.h/mL) | 4664 (3808-5664) | 10462 (8972-12200) | 1625 (1390-1899) |