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Table 1

From: Maraviroc (MVC) increases CD4+ and CD8+ cells: long-term data from the MVC clinical development program

Population Treatment-experienced Treatment-naive
Study MOTIVATE – 96 Weeks MERIT – 96 Weeks 1078 – 24 Weeks
Arm MVC QD MVC BID PBO MVC BID EFV MVC QD TDF/FTC
N 414 426 209 360 361 60 61
BL HIV RNA (median log10 cp/mL) 4.86 4.85 4.86 4.88 4.85 4.59 4.66
Baseline CD4 count (median cells/µL) 171 167 171 244.3 258.5 344.5 358.0
Baseline CD8 count (median cells/µL) 867.5 836.5 820.8 791.5 860.0 859.8 890.0
CD4 change from BL (median cells/µL) 89.0 112.5 21.0 224.3 195.0 195.3 173.0
CD8 change from BL (medican cells/µL) 138.0 157.0 31.5 -3.00 -94.5 4.5 -78.5