Table 1
Population | Treatment-experienced | Treatment-naive | |||||
|---|---|---|---|---|---|---|---|
Study | MOTIVATE – 96 Weeks | MERIT – 96 Weeks | 1078 – 24 Weeks | ||||
Arm | MVC QD | MVC BID | PBO | MVC BID | EFV | MVC QD | TDF/FTC |
N | 414 | 426 | 209 | 360 | 361 | 60 | 61 |
BL HIV RNA (median log10 cp/mL) | 4.86 | 4.85 | 4.86 | 4.88 | 4.85 | 4.59 | 4.66 |
Baseline CD4 count (median cells/µL) | 171 | 167 | 171 | 244.3 | 258.5 | 344.5 | 358.0 |
Baseline CD8 count (median cells/µL) | 867.5 | 836.5 | 820.8 | 791.5 | 860.0 | 859.8 | 890.0 |
CD4 change from BL (median cells/µL) | 89.0 | 112.5 | 21.0 | 224.3 | 195.0 | 195.3 | 173.0 |
CD8 change from BL (medican cells/µL) | 138.0 | 157.0 | 31.5 | -3.00 | -94.5 | 4.5 | -78.5 |