Endpoint | HIV tropism (g2p) | Treatment arm | ||||||
---|---|---|---|---|---|---|---|---|
R5 | X4 | p(uni) | p(multi) | ATZ/r | NVP | p(uni) | p(multi) | |
Week 24 | ||||||||
% of patients with VL<50 copies/mL | 83.2 | 60.9 | 0.001 | 0.012 | 77.2 | 82.1 | 0.281 | 0.384 |
CD4 gain (cells/mm3) | 116[56-197] | 117[66-172] | 0.979 | 0.439 | 116[72-203] | 111[45-111] | 0.316 | 0.173 |
Week 48 | ||||||||
% of patients with VL<50 copies/mL | 91.6 | 76.9 | 0.009 | 0.061 | 88.5 | 92.0 | 0.340 | 0.434 |
CD4 gain (cells/mm3) | 156[83-244] | 180[86-235] | 0.729 | 0.616 | 180[99-251] | 152[78-230] | 0.037 | 0.008 |