Table 2 Family-centred PMTCT intervention models: Extension of ART services
From: Family-centred approaches to the prevention of mother to child transmission of HIV
Citation, country, sample size | Design | Target group | Family-centred PMTCT programme components | Outcomes | Study limitations |
|---|---|---|---|---|---|
[24] Byakika Tusiime et al, 2009; Uganda; 177 individuals | Prospective cohort | Families | At one MTCT-Plus Initiative site in Uganda, treatment and therapy for mothers and HIV-infected family members was provided, including basic treatment of HIV-related opportunistic infections, as well as provision of antiretroviral therapy (ART) | In this family-centred model, near perfect adherence to ART was observed: mean adherence in studied groups ranged from 87.7% to 100% Among adults, depression was significantly associated with incomplete adherence (p = 0.04; OR = 0.32; 95% CI 0.11-0.93) | Information was not collected on the time gap between delivery and initiation of therapeutic treatment |
[25] Tonwe-Gold et al, 2009; Côte d'Ivoire; 605 women and 582 infants | Prospective cohort | Families | Through the MTCT-Plus Initiative, HIV prevention and care for family members, including clinical ART services Involvement and support of partners and children | Among cohort of 568 women with a living spouse, 53% disclosed HIV status to their male partner Enrolment of HIV-positive male partners was low (12%) Retention of individuals on ART was high (2.5% index women, 5.5% index partners lost to follow up) | Non-disclosure rates to partners remained high, even in the context of ART access Limited access to children outside the ANC context |