Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors

Petoumenos, Kathy; Hui, Eugenie; Kumarasamy, Nagalingeswaran; Kerr, Stephen J; Choi, Jun Yong; Chen, Yi-Ming A; Merati, Tuti; Zhang, Fujie; Lim, Poh-Lian; Sungkanuparph, Somnuek; Pujari, Sanjay; Ponnampalavanar, Sasheela; Ditangco, Rosanna; Lee, Christopher KC; Grulich, Andrew; Law, Matthew G

doi:10.1186/1758-2652-13-51

Journal of the International AIDS Society

Table 3 Factors associated with ADC

From: Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors

	Controls	Cases	OR	95%	CI	p-value	p-overall	OR	95%	CI	p-value	p-overall
Total	264	134
Age per 5 years	39.2 (10.9)	38.5 (9.9)	0.969	0.871	1.079	0.57
Male	179	96
Female	85	38	0.77	0.44	1.32	0.340
Homosexual	26	25
Heterosexual	202	89	0.35	0.18	0.72	0.004	0.005	0.35	0.16	0.73	0.005	0.007
IDU	17	4	0.18	0.05	0.67	0.010		0.17	0.04	0.69	0.013
Other	19	16	1.05	0.44	2.51	0.911		1.14	0.44	2.96	0.784
Chinese	82	41
Indian	94	44	0.24	0.03	2.08	0.196	0.328
Other	88	49	1.25	0.55	2.83	0.590
No prior AIDS	106	45
Prior AIDS	124	63	1.31	0.81	2.13	0.273	0.247
Missing	34	26	4.25	1.52	11.89	0.006
CDC A	62	25
CDC B	54	11	0.59	0.24	1.48	0.263	0.002	0.57	0.21	1.52	0.258	0.058
CDC C	137	94	2.18	1.06	4.51	0.035		1.73	0.76	3.94	0.191
Missing	11	4	1.26	0.31	5.10	0.746		0.75	0.16	3.57	0.713
CD4 cells/mm ³
<= 100	47	42
101-200	26	24	0.84	0.41	1.72	0.637	<0.001	0.73	0.34	1.55	0.412	<0.001
201-350	51	13	0.20	0.09	0.45	<0.001		0.16	0.06	0.38	<0.001
>= 351	60	14	0.20	0.09	0.43	<0.001		0.21	0.09	0.46	<0.001
Missing	80	41	0.60	0.30	1.17	0.133		0.54	0.27	1.09	0.085
Smoking
Never	125	70
Ever	83	41	0.86	0.50	1.48	0.583	0.357
Missing	56	23	0.60	0.30	1.21	0.155
Alcohol
Never	141	71
Ever	67	40	1.22	0.70	2.13	0.475	0.271
Missing	56	23	0.64	0.31	1.31	0.218
HBVS positive	149	70
HBVS negative	9	5	1.21	0.36	4.00	0.758	0.558
Missing	106	59	1.34	0.78	2.28	0.288
HCV positive	117	55
HCV negative	12	5	0.93	0.31	2.75	0.890
Missing	135	74	1.39	0.79	2.45	0.255
ART
Never	48	26
Ever/not current	14	12	1.58	0.66	3.78	0.304	0.126
Current	186	83	0.80	0.47	1.37	0.420
Missing	16	13	1.86	0.67	5.18	0.235

ART: antiretroviral treatment; IDU: Injecting drug user

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