Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe

Table 2 Change in barrier method(s) use at last sex, by visit type and by study groups

Change in condom use and use of any barrier method at last sex, among condom group participants (n = 420)
Last MIRA Follow-up Visit		Last FU visit		Post-trial visit		AOR	Lower limit	Upper limit	p value
		n	%	n	%
model 1	Condom use at last sex	363	86.43	283	67.38
	Visit type*					0.20	0.12	0.33	< 0.0001
	Time since trial exit					0.95	0.88	1.03	0.228
	Number of MIRA visits					1.01	0.84	1.22	0.8899
model 2	Any barrier method	374	89.05	312	74.29
	Visit type*					0.21	0.12	0.35	< 0.0001
	Time since trial exit					0.96	0.88	1.05	0.347
	Number of MIRA visits					0.93	0.75	1.16	0.5293

MIRA Enrolment Visit		Enrolment visit		Post-trial visit		AOR	Lower limit	Upper limit	p value
		n	%	n	%
model 1	Condom use at last sex	310	73.81	283	67.38
	Visit type**					0.66	0.46	0.93	0.0196
	Time since trial exit					0.96	0.90	1.02	0.1824
	Number of MIRA visits					1.07	0.91	1.25	0.4349
model 2	Any barrier method	323	76.9	312	74.29
	Visit type**					0.83	0.58	1.19	0.3178
	Time since trial exit					0.96	0.90	1.02	0.2077
	Number of MIRA visits					1.02	0.87	1.20	0.7732

Change in diaphragm, condom use and use of any barrier method at last sex, among diaphragm group participants (n = 381)
Last MIRA Follow-up Visit		Last FU visit		Post-trial visit		AOR	Lower limit	Upper limit	p value
		n	%	n	%
model 1	Diaphragm at last sex	303	79.53	192	50.39
	Visit type*					0.18	0.12	0.28	< 0.0001
	Time since trial exit					0.95	0.89	1.01	0.1058
	Number of MIRA visits					1.28	1.09	1.49	0.0024
model 2	Condom use at last sex	231	60.63	214	56.17
	Visit type*					0.77	0.55	1.09	0.1425
	Time since trial exit					1.03	0.96	1.10	0.4054
	Number of MIRA visits					1.26	1.07	1.49	0.0062
model 3	Any barrier method	357	93.7	285	74.8
	Visit type*					0.15	0.08	0.27	< 0.0001
	Time since trial exit					0.93	0.86	1.00	0.0593
	Number of MIRA visits					1.29	1.07	1.55	0.0072

MIRA Enrolment Visit		Enrolment visit		Post-trial visit		AOR	Lower limit	Upper limit	p value
		n	%	n	%
model 1	Condom use at last sex	259	67.98	214	56.17
	Visit type**					0.55	0.39	0.76	0.0004
	Time since trial exit					0.99	0.94	1.05	0.7865
	Number of MIRA visits					1.18	1.03	1.36	0.0153
model 2	Any barrier method	267	70.08	285	74.8
	Visit type**					1.33	0.93	1.89	0.1134
	Time since trial exit					0.96	0.90	1.02	0.1764
	Number of MIRA visits					1.16	1.00	1.34	0.0553

AOR = adjusted odds ratio; CL = confidence limit; FU = follow up
*post-trial visit vs. last MIRA follow-up visit
**post trial visit vs. MIRA enrolment visit
All models are controlling for age and substudy interview mode group (ACASI vs. FTF I)