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Table 1 Characteristics of 1826 eligible HIV-positive King's College Hospital patients between 1 January 1997 and 31 December 2005 on ≥ 1 occasionǂ

From: High rate of loss to clinical follow up among African HIV-infected patients attending a London clinic: a retrospective analysis of a clinical cohort

 

CCAs

TRANSFERS

UKLFU

P value

 

n = 1125*

n = 335*

n = 366*

 

Median age at HIV clinic registration (years) (IQR)

33 (27-38)

30 (26-35)

31 (26-36)

< 0.001

Gender-ethnicity risk group

n = 1119

n = 314

n = 352

 

   White MSM

261 (23.3%)

123 (39.2%)

50 (14.2%)

 

   Black African/Caribbean MSM

48 (4.3%)

12 (3.8%)

9 (2.6%)

 

   Black African heterosexual female

362 (32.4%)

72 (22.9%)

123 (34.9%)

 

   Black African heterosexual male

175 (15.6%)

35 (11.2%)

75 (21.3%)

< 0.001

   Black Caribbean heterosexual female

43 (3.8%)

6 (1.9%)

14 (4.0%)

 

   Black Caribbean heterosexual male

39 (3.5%)

2 (0.6%)

16 (4.6%)

 

   White heterosexual female

33 (2.9%)

13 (4.1%)

8 (2.3%)

 

   White heterosexual male

36 (3.2%)

7 (2.2%)

8 (2.3%)

 

   Other†

122 (10.9%)

44 (14.0%)

49 (13.9%)

 

Year of HIV clinic registration

    

   1997-1999

219 (19.5%)

95 (28.4%)

103 (28.1%)

 

   2000-2002

353 (31.4%)

142 (42.4%)

158 (43.2%)

< 0.001

   2003-2005

553 (49.2%)

98 (29.2%)

105 (28.7%)

 

Median baseline† CD4 cell count, cells/mm 3 (IQR) cells/mm 3

289 (134-459)

322 (194-480)

348 (145-523)

0.001

Baseline** CDC stage

n = 1125

n = 303

n = 322

 

   Asymptomatic

734 (65.2%)

185 (61.1%)

224 (69.6%)

0.091

   Symptomatic

232 (20.6%)

80 (26.4%)

61 (18.9%)

 

   AIDS

159 (14.1%)

38 (12.5%)

37 (11.5%)

 

Received HAART within 6 months of last visit

834 (74.1%)

118 (35.2%)

125 (34.2%)

< 0.001

Median CD4 cell count at last visit, cells/mm 3 (IQR)

410 (299-559)

376 (229-520)

368 (229-551)

< 0.001

% with CD4 cell count < 200 cells/mm 3 at last visit

n = 1112

n = 246

n = 289

 
 

109 (9.8%)

48 (19.5%)

64 (22.2%)

< 0.001

Median log viral load, copies/ml, at last visit (IQR)

1.6 (1.6-2.3)

3.7 (1.7-4.7)

3.5 (2.0-4.3)

< 0.001

% with VL ≤ 400 copies/ml at last attendance

n = 1109

n = 235

n = 266

< 0.001

 

855 (77.1%)

88 (37.4%)

90 (33.8%)

 

Median duration of clinic attendance (months)

46.2 (26.3-72.3)

7.7 (1.2-24.3)

4.1 (0.7-19.1)

< 0.001

Number of clinic visits in year prior to last clinic visit

n = 1114

n = 326

n = 362

 

   ≤ 2

25 (2.2%)

104 (31.9%)

149 (38.4%)

< 0.001

  1. All percentages are column percentages; Ç‚ of the original 1,859 patients, 33 were deceased (9 UKLFU patients, 12 Transfers and 12 CCAs) and excluded from further analysis, leaving 1826 patients.
  2. * Denominator values may differ due to missing data; † "other" gender-ethnic-risk group includes MSM and heterosexuals from other ethnic groups, such as Asian, black other, mixed (n = 122), and patients who acquired HIV through intravenous drug use (n = 82) and blood products/surgery (n = 6). ** Baseline refers to the first CD4 measurement and first reported CDC stage.
  3. CCAs: current clinic attendees. Transfers: patients not seen at the KCH HIV clinic for at least 1 year, but who subsequently have been seen elsewhere for HIV treatment/care services in the UK. UKLFU: patients not seen at the King's College Hospital HIV clinic for at least 1 year, who have not been seen anywhere else for HIV treatment/care services in the UK for at least a year.
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Journal of the International AIDS Society

ISSN: 1758-2652