Five-year follow up of genotypic resistance patterns in HIV-1 subtype C infected patients in Botswana after failure of thymidine analogue-based regimens

Table 5 Significant correlations of pairs of mutations within RT.

Group 1	Pearson coeff.	Jaccard coeff.	P value	Group 2	Pearson coeff.	Jaccard coeff.	P value
101E/190A	65.92	57.1	0.005	101E/190A	36.8	30	0.06
101E/219Q	46.55	40	0.034	106M/139A	40.32	33.3	0.04
102R/53D	51.3	40	0.05	106M/138A	39.3	33.3	0.04
103N/178L	46	40	0.03	106M/179E	46.9	37.5	0.02
106M/283I	63.9	50	0.005	108I/208Y	49.85	37.5	0.02
190A/69D	65.9	50	0.008	181C/67N	42.2	40	0.01
				181C/69D	64.9	50	0.001
				181C/98S	63.8	54.5	0.001
142V/158S	52.5	42.8	0.03	181C/228R	72.6	66.6	0.0001
178L/135V	52.5	44.4	0.02
221Y/162C	51.3	40	0.05	190A/41L	47.9	33.3	0.007
221Y/181C	66	50	0.008	190A/210W	41.5	33.3	0.04
228R/190A	52.7	33.3	0.05	190A/215Y	43.5	33.3	0.02
251D/53D	58.4	60	0.004	190A/74L	46.9	37.5	0.02
278N/60I	62.3	50	0.03
283I/102R	70.4	60	0.006	228R/98S	48	41.7	0.009
294T/102R	67.7	50	0.02	228R/215F	40	40	0.04
				210W/215Y	44.07	38.4	ND
210W/215Y	36.4	33.3	ND	41L/215Y	42.64	44.4	ND
41L/215Y	41.3	40	ND	41L/210W	44.4	37.5	ND
41L/210W	36.4	33.3	ND	41L/53D	31.7	25	ND
41L/53D	59.5	42.8	ND	41L/74V/I	53	40	ND
67N/70R	62.37	61.5	ND	67N/70R	54.05	56	ND
70R/219Q	83.01	80	ND	70R/219Q	65.53	64.7	ND
219Q/67D	62.37	61.5	ND	219Q/67D	54.05	56	ND
215F/67D	40.85	35.7	ND	215F/67D	45.06	44	ND
215F/70R	36.9	33.3	ND	215F/70R	34.6	38.9	ND
219Q/69N/D	49.64	33.3	ND	219Q/69N/D	34.36	27	ND