Table 3 Validity statistics using four methods for determining an HIV- and AIDS-related death, Botswana Vital Registration System, 2005
Gold standard definition | Post-test probability given negative testa | Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) | "True" prevalence |
|---|---|---|---|---|---|---|
Method A: physician consensus | 30.9 (29.2-32.7) | 55.7 (54.2-57.3) | 97.3 (96.0-98.7) | 95.4 (93.0-97.7) | 69.1 (67.3-70.8) | 49.6 (48.2-51.0) |
Method B: experts reviewb | 29.5 (27.8-31.3) | 55.7 (54.0-57.3) | 94.9 (93.2-96.6) | 90.7 (87.5-94.0) | 70.5 (68.8-72.2) | 47.3 (45.7-48.8) |
Method C: experts reviewc | 30.5 (28.8-32.3) | 54.8 (53.2-56.5) | 94.8 (93.1-96.5) | 90.7 (87.5-94.0) | 69.5 (67.7-71.2) | 48.0 (46.5-49.6) |
Method D: experts reviewd | 37.1 (35.3-38.9) | 50.4 (48.9-51.9) | 95.2 (93.5-97.0) | 92.3 (89.3-95.2) | 62.9 (61.1-64.7) | 53.1 (51.6-54.7) |