From: Sang Froid in a time of trouble: is a vaccine against HIV possible?
Following exposure, vaccinees had exaggerated disease in lungs. |
Pathology included immune complex deposition and high replication in the lungs. |
Vaccines elicited non-protective, low avidity, waning antibodies. |
Vaccines elicited strong CD4+ proliferation with a Th2 cytokine response, including IL-13 |
Caused cessation of use of both vaccines |