Table 1 cART efficacy
From: cART in vertically HIV-infected children treated since infancy
ART before HAART era (before 1998) | Initial cART started without resistance testing | Initial cART based on resistance reports | |
|---|---|---|---|
No.of children | 6 | 10 | 11 |
Current age | 10–14 yr (mean 12 yr) | 10 mo – 10 yr (mean 6 yr) | 2–7 yr (mean 4, 5 yr) |
The first regimen | NRTI | cART | cART |
No. of cART regimens | 2–3 | 1–5 | 1–3 |
No. of children receiving their first regimen currently | 0 | 3 | 3 |
No. of children with VL<50 c/ml at evaluation | 6 | 10 | 9 |
No. of patients with resistance testing before changing of ART | 2 | 4 | 2 |
Single class resistance development | 2 children (NRTI) | 1 child (PI) | 1 child (NRTI) |
Double class resistance development | 1 child (PI+NNRTI) | ||
Triple class resistance development | 2 children | 1 child |