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Table 1

From: O332 Opportunistic infections in immunocompromised but virologically suppressed HIV-1 infected patients

 

VL <500 c

VL ≥500 c

VL ≥500 nc

PYFU

3507

4274

934

Number of OIs

104

414

223

Crude event rate (95% CI)

3.0 (2.4–3.5)

9.7 (8.8–10.6)

23.9 (20.8–27.0)

Adjusted rate ratio (95% CI)

1.0

1.9 (1.5–2.4)

4.3 (3.3–5.7)

5 most commonly occurring OIs, n (% of all OIs):

   

Oesophageal candidiasis

11 (11%)

70 (17%)

50 (22%)

PCP

6 (6%)

11 (3%)

21 (9%)

Cytomegalovirus (CMV) chorioretinitis

2 (2%)

38 (9%)

11 (5%)

HIV wasting syndrome

6 (6%)

27 (7%)

11 (5%)

Mycobacterial tuberculosis, pulmonary

6 (6%)

22 (5%)

13 (6%)

Number of deaths

86

104

259

Crude event rate (95% CI)

2.5 (1.9–3.0)

2.4 (2.0–2.9)

27.7 (24.4–31.1)

Adjusted rate ratio (95% CI)

1.0

0.7 (0.5–1.0)

8.5 (6.4–11.1)

Median (IQR)

   

Calendar time of follow-up

09/01 (06/99-06/04)

04/00 (07/98-02/03)

01/01 (03/99-08/03)

CD4 count (/cells/mm3)

148 (109–178)

118 (61–160)

108 (50–158)

VL (log10 copies/mL)

1.7 (1.7–2.3)

4.4 (3.6–5.0)

4.9 (4.3–5.4)