Table 2 Factors associated with the use of D4T in the first ART regimen in multivariable analysis using log-link Poisson model with robust standard errors.

Male sex*

17, 173

0.97

0.95-0.99

< 0.001

Year of ART initiation (per 2 years)

0.81

0.73-0.89

< 0.001

Country of residence

   Kenya

33, 680

ref

   Uganda

10, 859

0.49

0.33-0.72

< 0.001

   Tanzania

4119

1.14

1.09-1.21

< 0.001

Age at ART initiation (years)

   Quartile 1 (18-31)

13, 152

ref

   Quartile 2 (32-37)

12, 766

1.00

0.99-1.02

0.58

   Quartile 3 (38-43)

10, 662

1.00

0.99-1.03

0.52

   Quartile 4 (44-88)

12, 078

0.99

0.97-1.02

0.56

WHO stage⁺

   Stage 1

7263

ref

   Stage 2

9808

1.01

0.98-1.05

0.52

   Stage 3

21, 291

1.06

1.02-1.11

< 0.01

   Stage 4

7648

1.10

1.02-1.07

0.01

Pre-therapy CD4 level^±

   ≤ 50 cells/mm³

10, 148

ref

   51-100 cells/mm³

7377

0.97

0.89-1.06

0.27

   101-200 cells/mm³

14, 528

0.87

0.81-0.94

0.09

   > 200 cells/mm³

16, 605

0.86

0.80-0.93

0.02

Presence of tuberculosis

0.94

0.90-0.98

< 0.01