Table 3 Multivariate logistic regression showing risk factors for LBW in HAART-exposed women irrespective of infant HIV status
Variable | Low Birth Weight (<2500 g) | |||||
|---|---|---|---|---|---|---|
Early HAART | Late HAART | |||||
Univariate analysis | Multivariate analysis (n = 341) | Univariate analysis | Multivariate analysis (n = 343) | |||
OR (95% CI) | AOR (95% CI) | P | OR (95% CI) | AOR (95% CI) | P | |
HAART-unexposed | 1.00 | 1.00 | 1.00 | 1.00 | ||
HAART-exposed | ||||||
PI-based | 0.58 (0.33-1.07) | 0.45 (0.19-1.06) | 0.068 | 0.58 (0.36-0.93) | 0.52 (0.28-0.98) | 0.04 |
NVP-based | 0.58 (0.33-1.01) | 0.38 (0.18-0.81) | 0.01 | 0.76 (0.40-1.41) | 0.70 (0.33-1.47) | 0.34 |
EFV-based | 1.86 (1.06-3.28) | 1.02 (0.46-2.25) | 0.96 | 0.73 (0.19-2.71) | 0.51 (0.10-2.72) | 0.43 |
CD4 cell count | ||||||
per category increase* | 0.71 (0.60-0.83) | 0.57 (0.45-0.71) | <0.001 | 0.94 (0.79-1.13) | 0.91 (0.73-1.15) | 0.45 |
Maternal age | ||||||
16-24 years | 1.0 | 1.0 | 1.0 | 1.0 | ||
25-29 years | 1.24 (0.67-2.28) | 0.80 (0.35-1.83) | 0.60 | 0.96 (0.53-1.74) | 0.98 (0.45-2.15) | 0.96 |
30-34 years | 1.45 (0.80-2.62) | 1.19 (0.54-2.58) | 0.67 | 1.26 (0.72-2.24) | 0.81 (0.37-1.76) | 0.60 |
≥35 years | 2.02 (1.03-3.96) | 1.71 (0.70-4.16) | 0.24 | 1.40 (0.72-2.73) | 1.62 (0.70-3.73) | 0.26 |
Hypertension | ||||||
no | 1.00 | 1.00 | 1.00 | 1.00 | ||
yes | 2.47 (1.18-5.17) | 2.10 (0.92-4.82) | 0.08 | 1.12 (0.48-2.60) | 0.97 (0.40-2.36) | 0.94 |
Infant PCR | ||||||
Negative | 1.00 | 1.00 | 1.00 | 1.00 | ||
Positive | 2.54 (1.30-4.96) | 3.28 (1.20-8.97) | 0.020 | 1.93 (0.09-3.43) | 2.37 (1.17-4.79) | 0.02 |